ChemicalBook >> CAS DataBase List >>3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate
3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate
- CAS No.
- 59256-52-9
- Chemical Name:
- 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate
- Synonyms
- Einecs 261-677-8;Bis-acrylate-PEG5;3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate;Bispropenoic acid 3,6,9,12-tetraoxatetradecane-1,14-diyl ester;14-(prop-2-enoyloxy)-3,6,9,12-tetraoxatetradecan-1-yl prop-2-enoate;2-Propenoic acid,3,6,9,12-tetraoxatetradecane-1,14-diyl ester (9CI);2-Propenoic acid, 1,1'-(3,6,9,12-tetraoxatetradecane-1,14-diyl) ester
- CBNumber:
- CB5930722
- Molecular Formula:
- C16H26O8
- Molecular Weight:
- 346.37
- MDL Number:
- MFCD32706469
- MOL File:
- 59256-52-9.mol
Last updated:2023-02-23 14:24:01
3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Chemical Properties,Uses,Production
Biological Activity
Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Preparation Products And Raw materials
Raw materials
Preparation Products
3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Suppliers
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3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate
Bispropenoic acid 3,6,9,12-tetraoxatetradecane-1,14-diyl ester
Einecs 261-677-8
2-Propenoic acid, 1,1'-(3,6,9,12-tetraoxatetradecane-1,14-diyl) ester
Bis-acrylate-PEG5
2-Propenoic acid,3,6,9,12-tetraoxatetradecane-1,14-diyl ester (9CI)
14-(prop-2-enoyloxy)-3,6,9,12-tetraoxatetradecan-1-yl prop-2-enoate
59256-52-9