ChemicalBook >> CAS DataBase List >>Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-
Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-
- CAS No.
- 1263131-83-4
- Chemical Name:
- Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-
- Synonyms
- MRT-14;N-(N-(3-Benzamidophenyl)carbamimidoyl)-3,4,5-trimethoxybenzamide;Inhibitor,Smo,Hedgehog,Smoothened,cancer,MRT 14,inhibit,MRT14,MRT-14;Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-
- CBNumber:
- CB610374786
- Molecular Formula:
- C24H24N4O5
- Molecular Weight:
- 448.47
- MDL Number:
- MOL File:
- 1263131-83-4.mol
Last updated:2024-07-02 08:55:12
Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Chemical Properties,Uses,Production
Biological Activity
MRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling[1].
References
[1]. Manetti F, et al. Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists. Mol Pharmacol. 2010;78(4):658-665.
Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Preparation Products And Raw materials
Raw materials
Preparation Products
Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Suppliers
Global( 6)Suppliers
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TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3732 | 55 |
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Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-
MRT-14
Inhibitor,Smo,Hedgehog,Smoothened,cancer,MRT 14,inhibit,MRT14,MRT-14
N-(N-(3-Benzamidophenyl)carbamimidoyl)-3,4,5-trimethoxybenzamide
1263131-83-4