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Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-

Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- structure

CAS No.: 1263131-83-4

Chemical Name:: Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-

Synonyms: MRT-14;N-(N-(3-Benzamidophenyl)carbamimidoyl)-3,4,5-trimethoxybenzamide;Inhibitor,Smo,Hedgehog,Smoothened,cancer,MRT 14,inhibit,MRT14,MRT-14;Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-

CBNumber:: CB610374786

Molecular Formula:: C24H24N4O5

Molecular Weight:: 448.47

MDL Number:

MOL File:: 1263131-83-4.mol

Last updated:2024-07-02 08:55:12

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Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Properties

Density	1.26±0.1 g/cm3(Predicted)
storage temp.	4°C, protect from light
solubility	DMSO : 100 mg/mL (222.98 mM; Need ultrasonic)
pka	10.28±0.46(Predicted)
form	Solid
color	Off-white to light yellow

Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Chemical Properties,Uses,Production

Biological Activity

MRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling[1].

References

[1]. Manetti F, et al. Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists. Mol Pharmacol. 2010;78(4):658-665.

Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3717	55
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	63720	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9294	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12007	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Bide Pharmatech Ltd.	58
TargetMol Chemicals Inc.	58
RD International Technology Co., Limited	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Spectrum

Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-(1263131-83-4)¹HNMR

Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- MRT-14 Inhibitor,Smo,Hedgehog,Smoothened,cancer,MRT 14,inhibit,MRT14,MRT-14 N-(N-(3-Benzamidophenyl)carbamimidoyl)-3,4,5-trimethoxybenzamide 1263131-83-4