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2-Maleimido acetic acid

2-Maleimido acetic acid structure

CAS No.: 25021-08-3

Chemical Name:: 2-Maleimido acetic acid

Synonyms: 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid;NSC 266055;N-Maleoylglycine;N-MaleiMidoglycine;N,N-maleoyl-glycine;MALEIMIDOACETIC ACID;2-maleimide acetic acid;2-MALEIMIDO ACETIC ACID;N-(CarboxyMethyl)MaleiMide;2-MALEIMIDO ACETIC ACID 97%

CBNumber:: CB61118111

Molecular Formula:: C6H5NO4

Molecular Weight:: 155.11

MDL Number:: MFCD00457254

MOL File:: 25021-08-3.mol

Last updated:2023-10-23 09:13:29

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2-Maleimido acetic acid Properties

Melting point	114 °C(Solv: chloroform (67-66-3))
Boiling point	376.7±25.0 °C(Predicted)
Density	1.578±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in DMSO, Methanol
form	powder to crystal
pka	3.31±0.10(Predicted)
color	White to Almost white
InChI	InChI=1S/C6H5NO4/c8-4-1-2-5(9)7(4)3-6(10)11/h1-2H,3H2,(H,10,11)
InChIKey	GBKPNGVKZQBPCZ-UHFFFAOYSA-N
SMILES	N1(CC(O)=O)C(=O)C=CC1=O

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335

Precautionary statements

P261-P280-P305+P351+P338

HS Code

2925.19.4200

NFPA 704

	0
2		0

2-Maleimido acetic acid price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M3143	2-Maleimidoacetic Acid >98.0%(HPLC)(T)	25021-08-3	50mg	$65	2024-03-01	Buy
TCI Chemical	M3143	2-Maleimidoacetic Acid >98.0%(HPLC)(T)	25021-08-3	250mg	$191	2024-03-01	Buy
TRC	M124990	MaleimidoaceticAcid	25021-08-3	250mg	$135	2021-12-16	Buy
Matrix Scientific	119970	2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid 95+%	25021-08-3	1g	$810	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0155638	2-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)ACETIC ACID 95.00%	25021-08-3	1G	$925.31	2021-12-16	Buy

Product number	Packaging	Price	Buy
M3143	50mg	$65	Buy
M3143	250mg	$191	Buy
M124990	250mg	$135	Buy
119970	1g	$810	Buy
CHM0155638	1G	$925.31	Buy

2-Maleimido acetic acid Chemical Properties,Uses,Production

Chemical Properties

White to Almost white powder to crystal or Pale Yellow Solid.

Uses

Maleimidoacetic Acid (CAS# 25021-08-3) is a heterocyclic organic compound that has a variety of uses in organic synthesis. It contains both a maleimide and carboxylic acid functional group, making it a versatile reagent for coupling reactions with amine-containing compounds.

Application

2-Maleimido acetic acid is a maleimide-containing ligand that could be used to produce the cisplatin-based Pt(IV) complexes (OC-6-44)-diamminedichlorido(ethanolato)(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV) and (OC-6-44)-acetatodiamminedichlorido(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV). The Pt(IV) complexes are considered to act as antitumor prodrugs and their in vivo activity can be improved by exploiting drug targeting and delivery strategies[1]. In this case, conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition.

References

[1] Gabano E, et al. Conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition. Inorganica Chimica Acta, 2019; 488: 195-200.

2-Maleimido acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

N-Succinimidyl maleimidoacetate

2-Maleimido acetic acid Suppliers

Global( 136)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2930	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
Shanghai Gubang New Materail Technology Co. LTD	21-51317962 +8618721305404	16728589@qq.com	CHINA	272	58
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	gksales1@gk-bio.com	China	9314	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19741	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3148	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Changzhou Ansciep Chemical Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
career henan chemical co	58
Shanghai Gubang New Materail Technology Co. LTD	58
Baoji Guokang Bio-Technology Co., Ltd.	58
BOC Sciences	58
Hangzhou Huarong Pharm Co., Ltd.	58

View Lastest Price from 2-Maleimido acetic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-07-13	2-Maleimido acetic acid 25021-08-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-09	2-Maleimido acetic acid 25021-08-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2020-01-09	2-Maleimido acetic acid 25021-08-3	US $9.80 / KG	1g	≥99%	100kg	Career Henan Chemical Co

2-Maleimido acetic acid
25021-08-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

2-Maleimido acetic acid
25021-08-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

2-Maleimido acetic acid
25021-08-3
US $9.80 / KG
≥99%
Career Henan Chemical Co

25021-08-3(2-Maleimido acetic acid)Related Search:

DISUCCINIMIDYL SUBERATE Suberate Bis(sulfosuccinimidyl) Sodium Salt N-Succinimidyl maleimidoacetate 3-(BENZOPHENONE-4-CARBOXAMIDO)-2-MALEIMIDOPROPANOIC ACID 2-Maleimido acetic acid

2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methanesulfonylbutanoic acid 2-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-PROPIONIC ACID 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-phenylpropanoic acid 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methylbutanoic acid DACM

3-MALEIMIDO-4-METHYL-6,7-METHYLENEDIOXYCOUMARIN RARECHEM AL CD 0491 4-carbamoyl-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methylpentanoic acid 9-ACETOXY-2-(4-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-3-OXO-3-H-NAPHTHO[2,1-B]PYRAN

2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-(1H-imidazol-4-yl)propanoic acid 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylpentanoic acid methyl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetate

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2-MALEIMIDOACETIC ACID DIHYDRATE N-Maleoylglycine 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-acetic Acid N-(CarboxyMethyl)MaleiMide N-MaleiMidoglycine NSC 266055 MAA 2-Maleimido acetic acid 2-MALEIMIDO ACETIC ACID 97% 2-(2,5-dioxopyrrol-1-yl)acetic acid 2-Maleimido acetic acid(MAA) 1H-Pyrrole-1-acetic acid, 2,5-dihydro-2,5-dioxo- 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid 2-maleimide acetic acid 2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-acetic acid MALEIMIDOACETIC ACID 2-MALEIMIDO ACETIC ACID N,N-maleoyl-glycine 25021-08-3 Organic Building Blocks Heterocycles Intermediates