ChemicalBook >> CAS DataBase List >>bermoprofen
bermoprofen
- CAS No.
- 78499-27-1
- Chemical Name:
- bermoprofen
- Synonyms
- AD-1590;Brn 4815717;10,11-DIHYDRO-α-8-DIMETHYL-11-OXO-DIBENZ(b,f)OXEPIN-2-ACETIC ACID;2-(8-Methyl-10,11-dihydro-11-oxodibenz(B,F)oxepin-2-yl)propionic;10,11-Dihydro-α,8-dimethyl-11-oxodibenz[b,f]oxepine-2-acetic acid;Propionic acid, 2-(8-methyl-10,11-dihydro-11-oxodibenz(B,F)oxepin-2-yl)-
- CBNumber:
- CB61383645
- Molecular Formula:
- C18H16O4
- Molecular Weight:
- 296.32
- MDL Number:
- MOL File:
- 78499-27-1.mol
Last updated:2024-07-02 08:55:12
| Melting point | 128-129° |
|---|---|
| Boiling point | 397.92°C (rough estimate) |
| Density | 1.1874 (rough estimate) |
| refractive index | 1.5400 (estimate) |
| storage temp. | Store at -20°C |
| form | Solid |
| color | Off-white to light yellow |
| FDA UNII | CWU66767HF |
bermoprofen Chemical Properties,Uses,Production
Originator
Bermoprofen,ZYF Pharm Chemical
Definition
ChEBI: Bermoprofen is a dibenzooxazepine.
Manufacturing Process
A mixture of dl-2-[4-(2'-carboxymethyl-4'-methylphenoxy)phenyl]propionic acid (15.3 g) and polyphosphoric acid (92 g) was heated with stirring at 110- 120°C for 2 hours. To the reaction mixture was added water and the resulting mixture was extracted with chloroform. The organic layer was washed with water, dried over anhydrous sodium sulfate and concentrated. The residue was chromatographed on silica gel (75 g) using chloroform as an eluent to give a crude product, which was recrystallized from toluene to give the dl-2-(8- methyl-10,11-dihydro-11-oxodibenz[b,f]oxepin-2-yl)propionic acid (9.4 g, 65.3%), m.p. 128-129°C.
Therapeutic Function
Antiinflammatory, Antipyretic
bermoprofen Preparation Products And Raw materials
bermoprofen Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 7432 | 58 |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18488 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 58 |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 58 |
10,11-Dihydro-α,8-dimethyl-11-oxodibenz[b,f]oxepine-2-acetic acid
AD-1590
2-(8-Methyl-10,11-dihydro-11-oxodibenz(B,F)oxepin-2-yl)propionic
Brn 4815717
Propionic acid, 2-(8-methyl-10,11-dihydro-11-oxodibenz(B,F)oxepin-2-yl)-
10,11-DIHYDRO-&alpha
-8-DIMETHYL-11-OXO-DIBENZ(b,f)OXEPIN-2-ACETIC ACID
78499-27-1