bermoprofen

bermoprofen 구조식 이미지
카스 번호:
78499-27-1
상품명:
bermoprofen
동의어(영문):
AD-1590;Brn 4815717;AD-1590|||AJ-1590;10,11-DIHYDRO-α-8-DIMETHYL-11-OXO-DIBENZ(b,f)OXEPIN-2-ACETIC ACID;2-(8-Methyl-10,11-dihydro-11-oxodibenz(B,F)oxepin-2-yl)propionic;10,11-Dihydro-α,8-dimethyl-11-oxodibenz[b,f]oxepine-2-acetic acid;Propionic acid, 2-(8-methyl-10,11-dihydro-11-oxodibenz(B,F)oxepin-2-yl)-
CBNumber:
CB61383645
분자식:
C18H16O4
포뮬러 무게:
296.32
MOL 파일:
78499-27-1.mol

bermoprofen 속성

녹는점
128-129°
끓는 점
397.92°C (rough estimate)
밀도
1.1874 (rough estimate)
굴절률
1.5400 (estimate)
저장 조건
Store at -20°C
물리적 상태
Solid
색상
Off-white to light yellow

안전

독성 LD50 in mice, rats (mg/kg): 500, 147 orally (Nakamura)

bermoprofen C화학적 특성, 용도, 생산

Originator

Bermoprofen,ZYF Pharm Chemical

Manufacturing Process

A mixture of dl-2-[4-(2'-carboxymethyl-4'-methylphenoxy)phenyl]propionic acid (15.3 g) and polyphosphoric acid (92 g) was heated with stirring at 110- 120°C for 2 hours. To the reaction mixture was added water and the resulting mixture was extracted with chloroform. The organic layer was washed with water, dried over anhydrous sodium sulfate and concentrated. The residue was chromatographed on silica gel (75 g) using chloroform as an eluent to give a crude product, which was recrystallized from toluene to give the dl-2-(8- methyl-10,11-dihydro-11-oxodibenz[b,f]oxepin-2-yl)propionic acid (9.4 g, 65.3%), m.p. 128-129°C.

Therapeutic Function

Antiinflammatory, Antipyretic

bermoprofen 준비 용품 및 원자재

원자재

준비 용품


bermoprofen 공급 업체

글로벌( 5)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd
027-88013699 17354350817
Ryan@jiutian-bio.com China 7432 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822
czbjpharma@126.com China 18488 58
TargetMol Chemicals Inc. 15002134094
marketing@targetmol.cn China 28118 58

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