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2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE

CAS No.
36341-25-0
Chemical Name:
2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE
Synonyms
Y109;Y-109;YL-109;Y-109;Y109;Phenol, 4-(2-benzothiazolyl)-2-methoxy-;4-(benzo[d]thiazol-2-yl)-2-Methoxyphenol;4-(1,3-Benzothiazol-2-yl)-2-methoxyphenol;2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE;4-(3H-1,3-benzothiazol-2-ylidene)-2-methoxycyclohexa-2,5-dien-1-one;inhibit,aryl,YL 109,hydrocarbon,AhR,antitumor,Aryl Hydrocarbon Receptor,YL109,carboxyl,breast,Hsp70-interacting,CHIP,protein,AhR,cancer,YL-109,terminus,invasiveness,Inhibitor
CBNumber:
CB61477104
Molecular Formula:
C14H11NO2S
Molecular Weight:
257.31
MDL Number:
MFCD00030231
MOL File:
36341-25-0.mol
Last updated:2024-11-19 20:33:22

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Properties

storage temp. 2-8°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml; Ethanol: 1 mg/ml
form A crystalline solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30290 YL-109 36341-25-0 5mg $110 2024-03-01 Buy
Cayman Chemical 30290 YL-109 36341-25-0 50mg $380 2024-03-01 Buy
Cayman Chemical 30290 YL-109 36341-25-0 10mg $195 2024-03-01 Buy
Cayman Chemical 30290 YL-109 36341-25-0 25mg $352 2024-03-01 Buy
AK Scientific 3261AH 4-(Benzo[D]thiazol-2-yl)-2-methoxyphenol 36341-25-0 1g $520 2021-12-16 Buy
Product number Packaging Price Buy
30290 5mg $110 Buy
30290 50mg $380 Buy
30290 10mg $195 Buy
30290 25mg $352 Buy
3261AH 1g $520 Buy

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Chemical Properties,Uses,Production

Biological Activity

YL-109 is a novel antitumor agent that inhibits the growth and invasion of breast cancer cells in vitro and in vivo.

in vitro

YL-109 (0.001-10 μM; 96 h or 24 h) inhibits cell proliferation, motility, and invasiveness in breast cancer cells.
YL-109 (1 μM) increases both CHIP mRNA and protein levels in MDA-MB-231 cells.

Cell Proliferation Assay

< td class="col2"> MCF-7 and MDA-MB-231 cells
Cell Line:
Concentration: 0.001, 0.01, 0.1, 1, 10 μM
Incubation Time: 96 hours
Result: Strongly inhibited cell proliferation of MCF-7 and MDA-MB-231 cells in a dose-dependent manner (IC 50 =85.8 nM and 4.02 μM, respectively).

in vivo

YL-109 (15 mg/kg; sc for every 2 d) inhibits both tumor growth and cancer metastasis of breast cancer cells in vivo.

< /p>

Animal Model: BALB/cAjcl-nu/nu female mice (4-5 weeks) inoculated with MCF-7 or MDA-MB-231 cells
Dosage: 15 mg/kg
Administration: < /td> Sc every 2 days for 63 days
Result: Suppressed tumor growth in mice injected with MCF-7 and MDA-MB-231 cells.

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 59)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30239 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66099280 17798518460 cfzhang@aikonchem.com China 19915 55
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7552 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58

View Lastest Price from 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
YL-109 pictures 2024-11-19 YL-109
36341-25-0
US $30.00-73.00 / mg ≥95% 10g TargetMol Chemicals Inc.
  • YL-109 pictures
  • YL-109
    36341-25-0
  • US $30.00-73.00 / mg
  • ≥95%
  • TargetMol Chemicals Inc.

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Spectrum

36341-25-0(2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE)Related Search:

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE YL-109 4-(benzo[d]thiazol-2-yl)-2-Methoxyphenol Y109 Y-109 Y-109;Y109 4-(3H-1,3-benzothiazol-2-ylidene)-2-methoxycyclohexa-2,5-dien-1-one 4-(1,3-Benzothiazol-2-yl)-2-methoxyphenol Phenol, 4-(2-benzothiazolyl)-2-methoxy- inhibit,aryl,YL 109,hydrocarbon,AhR,antitumor,Aryl Hydrocarbon Receptor,YL109,carboxyl,breast,Hsp70-interacting,CHIP,protein,AhR,cancer,YL-109,terminus,invasiveness,Inhibitor 36341-25-0 Inhibitors