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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE structure

CAS No.: 63-89-8

Chemical Name:: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Synonyms: DPPC;COLFOSCERIL PALMITATE;1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;16:0 PC;DIPALMITOYL LECITHIN;L-A-LECITHIN DIPALMITOYL;DIPALMITOYL-L-ALPHA-LECITHIN;B,G-DIPALMITOYL-L-A-LECITHIN;L-ALPHA-LECITHIN, DIPALMITOYL;1,2-dipalmitoyl-sn-glycero-3-PC

CBNumber:: CB6164209

Molecular Formula:: C40H80NO8P

Molecular Weight:: 734.04

MDL Number:: MFCD00036903

MOL File:: 63-89-8.mol

MSDS File:: SDS

Last updated:2024-11-20 11:41:24

Request For Quotation

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Properties

Melting point	229-229.5 °C
alpha	D23 +6.6° (c = 4.2 in 1:1 chloroform-methanol)
storage temp.	-20°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
Merck	14,2477
Stability	Stable. Incompatible with strong oxidizing agents.
InChIKey	KILNVBDSWZSGLL-KXQOOQHDSA-N
CAS DataBase Reference	63-89-8(CAS DataBase Reference)
FDA UNII	319X2NFW0A
ATC code	R07AA01

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS08

Signal word

Danger

Hazard statements

H302-H315-H319-H331-H336-H351-H361d-H372-H412

Precautionary statements

P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313

Safety Statements

24/25

WGK Germany

10-21

HS Code

29232000

NFPA 704

	0
3		0

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P0763	1,2-Dipalmitoyl-sn-glycero-3-phosphocholine semisynthetic, ≥99%	63-89-8	1g	$595	2024-03-01	Buy
Sigma-Aldrich	P0763	1,2-Dipalmitoyl-sn-glycero-3-phosphocholine semisynthetic, ≥99%	63-89-8	5g	$2520	2024-03-01	Buy
TCI Chemical	D3925	1,2-Dipalmitoyl-sn-glycero-3-phosphocholine >98.0%(HPLC)	63-89-8	200mg	$104	2024-03-01	Buy
TCI Chemical	D3925	1,2-Dipalmitoyl-sn-glycero-3-phosphocholine >98.0%(HPLC)	63-89-8	1g	$334	2024-03-01	Buy
Cayman Chemical	10009473	1,2-Dipalmitoyl-sn-glycero-3-PC ≥98%	63-89-8	25mg	$32	2024-03-01	Buy

Product number	Packaging	Price	Buy
P0763	1g	$595	Buy
P0763	5g	$2520	Buy
D3925	200mg	$104	Buy
D3925	1g	$334	Buy
10009473	25mg	$32	Buy

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Uses,Production

Description

DPPC, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine, is a phospholipid containing the 16 carbon fatty acid/palmitic acid (16:0) at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Due to the medium size of fatty acid chain, DLPC is used to form thinner membranes or lipid bilayers.

Chemical Properties

white powder

Uses

16:0 PC (DPPC) is suitable for use:

in vesicle preparation
as the main phospholipid component for all ultrasound contrast agents (UCA) formulations
as a component for microbubble preparation
in the preparation of lipid bilayers

Uses

16:0 PC (DPPC) has been used in the generation of thymoquinone (TQ) liposomes, gold nanorods and calcium chloride encapsulated liposomes and bilayers for biophysical studies.

Uses

1,2-dipalmitoyl-sn-glycero-3-phosphocholine is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).

Definition

ChEBI: A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.

General Description

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Purification Methods

It has three crystalline forms 1, 2 and ' which change at 60-70o and at 229o, respectively. In order to obtain a fine powder, ~2 g are dissolved in CHCl3 (15mL) and pet ether (b 35-60o) is added; the solution is evaporated to dryness in vacuo at <20o and then dried at 0.1mm over CaCl2. [Baer & Maurukas J Am Chem Soc 74 158 1952, Baer & Kates J Biol Chem 185 615 1950, Beilstein 4 IV 1463.]

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE synthesis

Synthesis of 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE from sn-Glycero-3-phosphocholine and Palmitic acid

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials

Raw materials

TYLOXAPOL Hexadecanoic acid, 1,1'-[1-[[(2-oxido-1,3,2-dioxaphospholan-2-yl)oxy]methyl]-1,2-ethanediyl] ester [S,(+)]-1-O,2-O-Dipalmitoyl-3-O-trityl-L-glycerol 2-CHLOROETHYLPHOSPHORIC ACID DICHLORIDE sn-Glycero-3-phosphocholine

1,2-DIPALMITOYL-SN-GLYCEROL Choline tosylate Palmitic acid Trimethylamine

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Preparation Products

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOBUTANOL (SODIUM SALT)

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers

Global( 284)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9206	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2930	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shochem(Shanghai) Co.,Ltd	86-21-50800795	info@shochem.com	CHINA	288	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Jinan Carbotang Biotech Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Shochem(Shanghai) Co.,Ltd	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
career henan chemical co	58

View Lastest Price from 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	DPPC 63-89-8	US $59.00-40.00 / mg		99.5%	10g	TargetMol Chemicals Inc.
2021-07-29	1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE USP/EP/BP 63-89-8	US $1.10 / g	1g	99.9%	100 Tons min	Dideu Industries Group Limited
2021-07-13	1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 63-89-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

DPPC
63-89-8
US $59.00-40.00 / mg
99.5%
TargetMol Chemicals Inc.

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE USP/EP/BP
63-89-8
US $1.10 / g
99.9%
Dideu Industries Group Limited

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
63-89-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Spectrum

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(63-89-8)¹HNMR 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(63-89-8)¹³CNMR

63-89-8(1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE)Related Search:

1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-DIHEPTADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE 1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-STEAROYL-2-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-PALMITOYL-2-STEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE 1,2-DINONADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE Lecithin

phosphorylcholine Palmitic acid Choline hydroxide L-ALPHA-LECITHIN 1,2-DIDOCOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1,2-DI 3,7,11,15-TETRAMETHYLHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 2,3-DIPALMITOYL-SN-GLYCERO-1-PHOSPHOCHOLINE 1,2-Dipalmitoyl-SN-Glycero-3-Phosphocholine-D9

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1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (R)-2,3-Bis(palMitoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate LIPOID PE 180/180-PEG 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine,1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, dipalmitoyl L-alpha-DipalMitoyl phosphatidylcholine, 98% 500MG (7R)-4-Hydroxy-N,N,N-triMethyl-10-oxo- 7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aMiniuM Inner Salt 4-Oxide 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine 1,2-Bis(pal 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine 2,3-Bis(palmitoyloxy)propyl [2-(Trimethylammonio)ethyl]phosphate L-b,g-DipalMitoyl-a-lecithin, DPPC DPPC L-1116 (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]- 3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt 1,2-Dihexadecanoyl-sn-glycero-3-phosphorylcholine 1,2-Dipalmitoyl-L-lecithin L-α-Phosphatidylcholine, dipalmitoyl L-β,γ-Dipalmi (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]- 3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine 1,2-Dihexadecanoyl-sn-glycero-3-phosph 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO L-alpha-Dipalmitoyl lecithin 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SEMISYNTHETIC 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SEMISYNTHETIC 1 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PH L-A-DIPALMITOYL LECITHIN L-a-Lecithin-b,g-dipalmitoyl=DilinoleoylLecithin=Dilinoleoyl-L-a-Lecithin=L-b,g-Dipalmitoyl-a-Lecithin LecithinL-a-Dipalmitoyl L-ALFA-PHOSPHATIDYLCHLOLINE, DIPALMITOYL (R)-(4-oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium 4-oxide [2-[(R)-2,3-Bis[(1-oxohexadecyl)oxy]propyloxyphosphinatooxy]ethyl]dimethylmethanaminium L-alpha-Dipalmitoyl phosphatidylcholine,98% Colfosceril 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-(1-oxohexadecyl)oxy-, inner salt, 4-oxide, (7R)- 3-sn-phosphatidylcholine, 1,2-dipalmitoyl 2-[[(2R)-2,3-dihexadecanoyloxypropoxy]-oxido-phosphoryl]oxyethyl-trimethyl-azanium Dipalmitoyl-L-ALPHA-phosphatidyl choline L-á-Phosphatidylcholine dipalmitoyl Dipalmitoyl-D62-SN-Glycero-3-Phospho-Choline 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, dipalmitoyl Coifosceril Palmitate Dipalmitoyl-L-α-glycerylphosphorylcholine ExosurfNeonatal 1,2-dipalmitoyl-sn-glycero-3-phosphocholine(DPPC) CAS_63-89-8 Dipalmitoyl sn 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (Colfosceril Palmitate) 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine> 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL 129Y83 16:0 PC (DPPC) L-A-PHOSPHATIDYLCHOLINE, DIPALMITOYL (DPPC) (DIPALMITOYL-D62, 98%) L-DPPC 2,3-Bis(palmitoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE USP/EP/BP 1,2-DIHEXADECANOYL-SN-GLYCERO-3- 1，2-dipalmitoyl-sn-glycero-3-phosphocholine,≥99% 1,2-dipalmitoyl-sn-glycero-3-phosphpcholine 63-89-8 C40H80NO8P 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 16:0 PC 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE