Reversan
- CAS No.
- 313397-13-6
- Chemical Name:
- Reversan
- Synonyms
- CBLC4H10;Reversan;Reversan, MRP1 and P-glycoprotein inhibitor;N-(3-Morpholinopropyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-;5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide;ReversanQ: What is Reversan Q: What is the CAS Number of Reversan Q: What is the storage condition of Reversan Q: What are the applications of Reversan
- CBNumber:
- CB61883226
- Molecular Formula:
- C26H27N5O2
- Molecular Weight:
- 441.52
- MDL Number:
- MFCD01528184
- MOL File:
- 313397-13-6.mol
Reversan price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0173 | Reversan ≥98% (HPLC) | 313397-13-6 | 5mg | $129 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0173 | Reversan ≥98% (HPLC) | 313397-13-6 | 25mg | $519 | 2024-03-01 | Buy |
| Tocris | 3722 | Reversan ≥99%(HPLC) | 313397-13-6 | 50 | $952 | 2021-12-16 | Buy |
| Tocris | 3722 | Reversan ≥99%(HPLC) | 313397-13-6 | 10 | $227 | 2021-12-16 | Buy |
| Usbiological | 256447 | Reversan | 313397-13-6 | 10mg | $480 | 2021-12-16 | Buy |
Reversan Chemical Properties,Uses,Production
Uses
Reversan represents a new class of nontoxic MRP1 inhibitor, which may be clinically useful for the treatment of neuroblastoma.
Biological Activity
Selective inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp). Increases the sensitivity of MRP1-overexpressing tumor cells (MCF7/VP) to doxorubicin , vincristine and etoposide by 3.8-, 14.6- and 11.6-fold respectively. Increases the efficacy of vincristine and etoposide in murine models of neuroblastoma in vivo . Displays at activity on MRP2, MRP3, MRP5 and MRP5 transporters.
storage
Store at -20°C
Reversan Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-18791163155 +86-13119157289 | 13119157289@163.com | China | 3558 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 | |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD | 13816107857 | sales@fortunechem-sh.com | China | 825 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 6039 | 55 |
