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Reversan

化学構造式
313397-13-6
CAS番号.
313397-13-6
化学名:
别名:
英語名:
Reversan
英語别名:
CBLC4H10;Reversan;Reversan, MRP1 and P-glycoprotein inhibitor;N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-;5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide;ReversanQ: What is Reversan Q: What is the CAS Number of Reversan Q: What is the storage condition of Reversan Q: What are the applications of Reversan
CBNumber:
CB61883226
化学式:
C26H27N5O2
分子量:
441.52
MOL File:
313397-13-6.mol

Reversan 物理性質

融点 :
176-180°C
比重(密度) :
1.26±0.1 g/cm3(Predicted)
貯蔵温度 :
Store at RT
溶解性:
DMSO: 約60°Cで8mg/mL以上
酸解離定数(Pka):
11.33±0.46(Predicted)
外見 :
粉
色:
淡い黄色～黄色

安全性情報

WGK Germany  3

Reversan 価格 もっと(4)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC3722
Reversan 		313397-13-6 10mg ￥80000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC3722
Reversan 		313397-13-6 50mg ￥335000 2024-03-01 購入
Sigma-Aldrich Japan SML0173 ≥98% (HPLC)
Reversan ≥98% (HPLC)		 313397-13-6 5mg ￥21500 2024-03-01 購入
Sigma-Aldrich Japan SML0173 ≥98% (HPLC)
Reversan ≥98% (HPLC)		 313397-13-6 25mg ￥108000 2024-03-01 購入

Reversan 化学特性,用途語,生産方法

使用

Reversan represents a new class of nontoxic MRP1 inhibitor, which may be clinically useful for the treatment of neuroblastoma.

生物活性

Selective inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp). Increases the sensitivity of MRP1-overexpressing tumor cells (MCF7/VP) to doxorubicin , vincristine and etoposide by 3.8-, 14.6- and 11.6-fold respectively. Increases the efficacy of vincristine and etoposide in murine models of neuroblastoma in vivo . Displays at activity on MRP2, MRP3, MRP5 and MRP5 transporters.

Reversan 上流と下流の製品情報

原材料

準備製品

Reversan 生産企業

Global( 51)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 		+86-18791163155 +86-13119157289
 13119157289@163.com China 2973 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 94657 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
 klq@cw-bio.com China 5933 55
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136
 Sales@ATKchemical.com China 7295 58
  • 313397-13-6
  • N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
  • Reversan
  • CBLC4H10
  • 5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide
  • Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-
  • ReversanQ: What is Reversan Q: What is the CAS Number of Reversan Q: What is the storage condition of Reversan Q: What are the applications of Reversan
  • Reversan, MRP1 and P-glycoprotein inhibitor
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