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ISOCORYDINE HYDROCHLORIDE

ISOCORYDINE HYDROCHLORIDE structure

CAS No.: 475-67-2

Chemical Name:: ISOCORYDINE HYDROCHLORIDE

Synonyms: luteanin;LUTEANINE;artabotrin;Aids138466;Uzokoridin;Isocorydine;Aids-138466;d-isocorydine;l-(+)-isocorydine;S-ISOCORYDINE (+)

CBNumber:: CB6238999

Molecular Formula:: C20H23NO4

Molecular Weight:: 341.4

MDL Number:: MFCD00075905

MOL File:: 475-67-2.mol

Last updated:2024-11-19 20:33:22

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ISOCORYDINE HYDROCHLORIDE Properties

Melting point	216-220 °C(lit.)
alpha	D20 +195° (chloroform)
Boiling point	477.03°C (rough estimate)
Density	1.2064 (rough estimate)
refractive index	1.5614 (estimate)
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Cryst.
pka	9.41±0.20(Predicted)
FDA UNII	3B5E87JEOX

SAFETY

Risk and Safety Statements

WGK Germany	3
RTECS	CE1057950
Toxicity	LD50 intraperitoneal in mouse: 104mg/kg

ISOCORYDINE HYDROCHLORIDE price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	30101	Isocorydine	475-67-2	10mg	$56	2024-03-01	Buy
Cayman Chemical	30101	Isocorydine	475-67-2	25mg	$116	2024-03-01	Buy
Cayman Chemical	30101	Isocorydine	475-67-2	5mg	$37	2024-03-01	Buy
Cayman Chemical	30101	Isocorydine	475-67-2	50mg	$178	2024-03-01	Buy
Usbiological	361810	Isocorydine	475-67-2	20mg	$546	2021-12-16	Buy

Product number	Packaging	Price	Buy
30101	10mg	$56	Buy
30101	25mg	$116	Buy
30101	5mg	$37	Buy
30101	50mg	$178	Buy
361810	20mg	$546	Buy

ISOCORYDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Isocorydine is an aporphine alkaloid that has been found in A. squamosa that has vasodilatory and anticancer activities. It reduces the action potential duration and increases the effective refractory period in isolated canine Purkinje fibers when used at a concentration of 30 μM. Isocorydine induces relaxation of norepinephrine-precontracted isolated rabbit aortic strips with an EC₅₀ value of 12.6 μM. It is cytotoxic to A549 lung cancer cells (IC₅₀ = 197.7 μM), as well as Huh7, HepG2, SNU-449, and SNU-387 hepatic cancer cells (IC₅₀s = 161.3, 148, 262.2, and 254.1 μg/ml, respectively). Isocorydine, in combination with doxorubicin, reduces tumor growth in a Huh7 mouse xenograft model.

Uses

Isocorydine is an alkaloid inhibitor of eukaryotic kinases.

Uses

sedative, cholinergic

Uses

Isocorydine Hydrochloride is the hydrochloric acid of Isocorydine(I797000) which is an alkaloid inhibitor of eukaryotic kinases.

Definition

ChEBI: Isocorydine is an aporphine alkaloid.

target

Dopamine Receptor | P450 (e.g. CYP17)

References

See Isocorydine

ISOCORYDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-MENISPERINE IODIDE

ISOCORYDINE HYDROCHLORIDE Suppliers

Global( 151)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
Chengdu Greenpure Biopharma CO.,Ltd	18283602253; +8618283602253	jancyzheng@gcgreenpure.com	China	953	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3772	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10319	58

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu Greenpure Biopharma CO.,Ltd	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei xin bonus chemical co. LTD	58
Shanghai Standard Technology Co., Ltd.	58
career henan chemical co	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58

View Lastest Price from ISOCORYDINE HYDROCHLORIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	Isocorydine 475-67-2	US $47.00-167.00 / mg		98.19%	10g	TargetMol Chemicals Inc.
2023-02-24	Isocorydine 475-67-2	US $0.00 / mg	20mg	≥98%(HPLC)	100 g	Shanghai Standard Technology Co., Ltd.
2020-01-10	ISOCORYDINE HYDROCHLORIDE 475-67-2	US $9.80 / KG	1KG	≥98%	20 tons	Career Henan Chemical Co

Isocorydine
475-67-2
US $47.00-167.00 / mg
98.19%
TargetMol Chemicals Inc.

Isocorydine
475-67-2
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

ISOCORYDINE HYDROCHLORIDE
475-67-2
US $9.80 / KG
≥98%
Career Henan Chemical Co

ISOCORYDINE HYDROCHLORIDE Spectrum

ISOCORYDINE HYDROCHLORIDE(475-67-2)¹HNMR

475-67-2(ISOCORYDINE HYDROCHLORIDE)Related Search:

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LUTEANINE LUTEANINE HYDROCHLORIDE 1,2,10-trimethoxy-6a-alpha-aporphin-11-o 4h-dibenzo(de,g)quinolin-11-ol,5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methy artabotrin d-isocorydine l-(+)-isocorydine luteanin luteanine(aporphine) D-ISOCORYDINE HYDROCHLORIDE (+)-ISOCORYDINE HCL ISOCORYDINE HCL, (+)- (+)-ISOCORYDINE HYDROCHLORIDE ISOCORYDINE HYDROCHLORIDE (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE HYDROCHLORIDE (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol [6aS,(+)]-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol Isocorydine S-ISOCORYDINE (+) 1,2,10-Trimethoxy-6-methyl-5,6,6A,7-tetrahydro-4H-dibenzo[de,G]quinolin-11-ol Aids138466 Aids-138466 Aporphin-11-ol, 1,2,10-trimethoxy- (+)-isocorynoline (+)-Isocorynoline hydrochloride Uzokoridin 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6aS)- Artabotrin|||S-Isocorydine(+)|||Luteanin|||Uzokoridin|||(+)-Isocorynoline 475-67-2 Analytical Chromatography Product Catalog Analytical Standards Asymmetric Synthesis Chiral Building Blocks Others Drug Standards Chromatography Forensic and Veterinary Standards Heterocyclic Building Blocks Inhibitors Miscellaneous Natural Products Alkaloids