ANTI-HUMAN CD42B
- CAS No.
- Chemical Name:
- ANTI-HUMAN CD42B
- Synonyms
- Anti-BSS;ANTI-GPIB;ANTI-GP1B;ANTI-CD42B;Anti-GP1BA;Anti-MGC34595;Anti-CD42balpha;ANTI-HUMAN CD42B;ANTI-CD42B, HUMAN;ANTI-GPLB MOUSE MAB
- CBNumber:
- CB6240769
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00675796
- MOL File:
- Mol file
ANTI-HUMAN CD42B price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4700955 | Monoclonal Anti-CD42b antibody produced in mouse clone AK2 | 100μg | $420 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4700290 | Monoclonal Anti-CD42b antibody produced in mouse clone HIP1, purified immunoglobulin, buffered aqueous solution | 100μg | $281 | 2024-03-01 | Buy |
ANTI-HUMAN CD42B Chemical Properties,Uses,Production
Uses
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2-8 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
General Description
The mouse monoclonal antibody AK2 recognizes CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c; 160 kDa); CD42b/c forms a noncovalent complex with CD42a and CD42d.
Biochem/physiol Actions
Cluster of differentiation 42b (CD42b) clustering promotes integrin αIIbβ3-dependent platelet aggregation, phagocytosis and rapid platelet clearance in the liver. The encoded protein acts as a platelet receptor for von Willebrand factor (VWF) and other ligands present in circulation. Mutation in the gene leads to autosomal recessive Bernard-Soulier syndrome. CD42b interacts with plasma hemoglobin (Hb) and enhances platelet activation and apoptosis in a concentration-dependent manner and also regulates platelet functions.
ANTI-HUMAN CD42B Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN CD42B Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Ruinuode Biotechnology Co., Ltd. | -- | 2090855807@qq.com | CHINA | 6063 | 58 |
| Nanjing Sai Ruirui Biotechnology Co., Ltd. | -- | sales@shrbio.com | CHINA | 6873 | 58 |
| Beijing Huaxia Ocean Technology Co., Ltd. | -- | huaxiabio@163.com | CHINA | 6122 | 58 |
| Shanghai Beinuo Biotechnology Co., Ltd. | -- | beinuobio@163.com | CHINA | 6580 | 58 |
| Beijing Bi Orange Blue Biotechnology Co., Ltd. | -- | bo49855987@163.com | CHINA | 6827 | 58 |
| Shanghai Minmin Biotechnology Co., Ltd. | -- | 1914109725@qq.com | CHINA | 6530 | 58 |
| Riedel-de Haen AG | -- | United States | 6825 | 87 | |
| EMD Biosciences, Inc. | -- | technical@calbiochem.com | United States | 6529 | 66 |
| BIOTREND Chemikalien GmbH | -- | jaeger@biotrend.com | Germany | 6115 | 76 |
| BD Biosciences | -- | United States | 5013 | 82 |