trans-Ned 19
- CAS No.
- 1354235-96-3
- Chemical Name:
- trans-Ned 19
- Synonyms
- trans-Ned 19;transNed 19,trans Ned 19;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]Methyl]-4-Methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)-
- CBNumber:
- CB62546793
- Molecular Formula:
- C30H31FN4O3
- Molecular Weight:
- 514.59
- MDL Number:
- MFCD20926336
- MOL File:
- 1354235-96-3.mol
trans-Ned 19 price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17527 | trans-Ned-19 ≥98% | 1354235-96-3 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 17527 | trans-Ned-19 ≥98% | 1354235-96-3 | 5mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 17527 | trans-Ned-19 ≥98% | 1354235-96-3 | 10mg | $321 | 2024-03-01 | Buy |
| Tocris | 3954 | trans-Ned19 ≥98%(HPLC) | 1354235-96-3 | 10 | $335 | 2021-12-16 | Buy |
| TRC | N388750 | trans-Ned-19 | 1354235-96-3 | 50mg | $1135 | 2021-12-16 | Buy |
trans-Ned 19 Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
trans-Ned-19 is a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells.
Definition
ChEBI: Trans-Ned 19 is a member of the class of beta-carbolines that is 2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid in which one of the methylene protons at position 1 has been replaced by a 3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-methoxyphenyl group. It has a role as a nicotinic acid adenine dinucleotide phosphate receptor antagonist. It is a member of beta-carbolines, an alpha-amino acid, a monomethoxybenzene, a member of monofluorobenzenes and a N-arylpiperazine.
storage
Store at -20°C
trans-Ned 19 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29795 | 68 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 56068 | 58 |