ChemicalBook >> CAS DataBase List >>PF 477736 (HCl)
PF 477736 (HCl)
- CAS No.
- 952238-93-6
- Chemical Name:
- PF 477736 (HCl)
- Synonyms
- PF 477736 (HCl);(alphaR)-alpha-Amino-N-[5,6-dihydro-2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]cyclohexaneacetamide hydrochloride
- CBNumber:
- CB62628235
- Molecular Formula:
- C22H26ClN7O2
- Molecular Weight:
- 455.95
- MDL Number:
- MFCD16038846
- MOL File:
- 952238-93-6.mol
Last updated:2023-05-04 17:34:44
PF 477736 (HCl) Chemical Properties,Uses,Production
Definition
ChEBI: PF-00477736 is a diazepinoindole that is 8-amino-4,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one which is substituted at position 2 by a 1-methylpyrazol-4-yl group and in which the amino group at position 8 has undergone condensation with the carboxy group of (2R)-2-cyclohexylglycine to give the corresponding carboxamide. It is an inhibitor of checkpoint kinase 1 (Chk 1). It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor and an antineoplastic agent. It is an amino acid amide, a member of pyrazoles and a diazepinoindole.
PF 477736 (HCl) Preparation Products And Raw materials
Raw materials
Preparation Products
PF 477736 (HCl) Suppliers
Global( 3)Suppliers
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PF 477736 (HCl)
(alphaR)-alpha-Amino-N-[5,6-dihydro-2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]cyclohexaneacetamide hydrochloride
952238-93-6
C22H25N7O2xHCl