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5-Ethynyl-2'-deoxycytidine

5-Ethynyl-2'-deoxycytidine Structure
5-Ethynyl-2'-deoxycytidine structure
CAS No.
69075-47-4
Chemical Name:
5-Ethynyl-2'-deoxycytidine
Synonyms
5-Ethynyl-2'-dC;-Ethynyl-2’5-Ethynyl-2'-deoxycytidine;2'-Deoxy-5-ethynylcytidine;5'-Ethynyl-2'-deoxycytidine;5-Ethynyl-2'-deoxycytidine>Cytidine, 2'-deoxy-5-ethynyl-;5-Ethynyl-2′-deoxycytidine, (EdC);5-Ethynyl-2'-deoxycytidine 69075-47-4;5-Ethynyl-2'-deoxycytidine, (EdC) AldrichCPR
CBNumber:
CB62682226
Molecular Formula:
C11H13N3O4
Molecular Weight:
251.24
MDL Number:
MFCD22417249
MOL File:
69075-47-4.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02
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5-Ethynyl-2'-deoxycytidine Properties

Melting point 191 °C (decomp)(Solv: dichloromethane (75-09-2); methanol (67-56-1))
Boiling point 475.7±55.0 °C(Predicted)
Density 1.54±0.1 g/cm3(Predicted)
storage temp. Store at 2-8°C, protect from light, stored under nitrogen
solubility DMF: 5 mg/ml; DMSO: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
pka 14.03±0.60(Predicted)
form powder to crystal
color White to Light yellow to Light orange
λmax 292nm(H2O)(lit.)
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
HS Code  2934.99.4400

5-Ethynyl-2'-deoxycytidine price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T511307 5-Ethynyl-2′-deoxycytidine, (EdC) AldrichCPR 69075-47-4 5mg $180 2024-03-01 Buy
TCI Chemical E1093 5-Ethynyl-2'-deoxycytidine >98.0%(N) 69075-47-4 50mg $203 2021-12-16 Buy
TCI Chemical E1093 5-Ethynyl-2'-deoxycytidine >98.0%(N) 69075-47-4 200mg $712 2024-03-01 Buy
Cayman Chemical 11581 5'-Ethynyl-2'-deoxycytidine ≥98% 69075-47-4 1mg $32 2024-03-01 Buy
Cayman Chemical 11581 5'-Ethynyl-2'-deoxycytidine ≥98% 69075-47-4 5mg $116 2024-03-01 Buy
Product number Packaging Price Buy
T511307 5mg $180 Buy
E1093 50mg $203 Buy
E1093 200mg $712 Buy
11581 1mg $32 Buy
11581 5mg $116 Buy

5-Ethynyl-2'-deoxycytidine Chemical Properties,Uses,Production

Description

5''-Ethynyl-2''-deoxycytidine (EdC) is a nucleoside analog that inhibits replication of the herpes simplex virus-1 (HSV-1) KOS strain (ID50 = 0.2 μg/mL). It also reduces virus-induced cytopathogenicity of HSV-1, HSV-2, and vaccinia virus strains in PRK cells (MICs = 0.2-0.4, 1-2, and 5 μg/ml, respectively). EdC is an inhibitor of thymidylate synthetase, selectively reducing DNA incorporation of [1'',2''-3H]deoxyuridine over [CH3-3H]deoxythymidine in PRK cells (ID50s = 3 and 120 μg/ml, respectively). It inhibits thymidine synthetase in and reduces proliferation of L1210 cells, an effect which is reversed by addition of deoxythymidine (ID50s = 4.4 and 1,000 μg/ml, respectively). EdC has been used to monitor DNA synthesis and cellular replication via click chemistry conjugation of the ethynyl group to an azido group of various fluorochromes.

Uses

5-Ethynyl-2’-deoxycytidine is an lower toxicity analog of 2’-deoxycytidine, a metabolic labeling probe for DNA synthesis. 5-Ethynyl-2’-deoxycytidine is most commonly used when thymidine analogs is undesirable.

Uses

A relatively nontoxic 2′-deoxycytidine analog for metabolic labeling of newly synthesized DNA in vivo. Especially suitable if the use of thymidine analogs is undesirable.

reaction suitability

reaction type: click chemistry

5-Ethynyl-2'-deoxycytidine Preparation Products And Raw materials

Raw materials

Preparation Products

5-Ethynyl-2'-deoxycytidine Suppliers

Global( 63)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29808 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9642 58
Wuhan Fortuna Chemical Co., Ltd 		+86-027-59207850 info@fortunachem.com China 5974 58
NewCan Biotech Limited 		+86-0571-86912261 +8613735419629 sales@newcanbio.com China 9985 58
Wuhu Nuowei chemistry Co., Ltd. 		+86-0553-2911116-802 +86-18055311600 sales1@nuowei-chem.com China 1638 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9297 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20235 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Supplier Advantage
BOC Sciences 		58
career henan chemical co 		58
Finetech Industry Limited 		58
Wuhan Fortuna Chemical Co., Ltd 		58
NewCan Biotech Limited 		58
Wuhu Nuowei chemistry Co., Ltd. 		58
Henan Aochuang Chemical Co.,Ltd. 		58
LEAPCHEM CO., LTD. 		58
Henan Fengda Chemical Co., Ltd 		58
Aladdin Scientific 		58

View Lastest Price from 5-Ethynyl-2'-deoxycytidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Ethynyl-2'-deoxycytidine pictures 2025-04-24 5-Ethynyl-2'-deoxycytidine
69075-47-4
 US $0.00-0.00 / g 10g 98%min 1000g WUHAN FORTUNA CHEMICAL CO., LTD
5-Ethynyl-2'-deoxycytidine pictures 2025-04-04 5-Ethynyl-2'-deoxycytidine
69075-47-4
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
5-Ethynyl-2'-deoxycytidine pictures 2020-03-05 5-Ethynyl-2'-deoxycytidine
69075-47-4
 US $1.00 / KG 1KG 98% HPLC 10 tons Career Henan Chemical Co
5-Ethynyl-2′-deoxycytidine, (EdC) Cytidine, 2'-deoxy-5-ethynyl- 2'-Deoxy-5-ethynylcytidine 5-Ethynyl-2'-deoxycytidine, (EdC) AldrichCPR 5-Ethynyl-2'-deoxycytidine 5-Ethynyl-2'-dC 4-Amino-5-ethynyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one -Ethynyl-2&rsquo 5-Ethynyl-2'-deoxycytidine> 5-Ethynyl-2'-deoxycytidine 69075-47-4 5'-Ethynyl-2'-deoxycytidine 5-Ethynyl-2''-deoxycytidine (5-EdC), DNA synthesis monitoring probe 69075-47-4 Carbohydrates & Derivatives, Heterocycles, Nucleotides, Bases & Related Reagents