LUZINDOLE
- CAS No.
- 117946-91-5
- Chemical Name:
- LUZINDOLE
- Synonyms
- N-0774;LUZINDOLE;Luzindole N;Luzindole, 10 mM in DMSO;Luzindole Solution, 100ppm;N-ACETYL-2-BENZYLTRYPTAMINE;2-Benzyl-N-acetyltryptaMine;LuzindoleN-Acetyl-2-benzyltryptamine;N-(2-(2-benzyl-1H-indol-3-yl)ethyl)acetamide;Luzindole (N-0774), melatonin receptor antagonist
- CBNumber:
- CB6268781
- Molecular Formula:
- C19H20N2O
- Molecular Weight:
- 292.37
- MDL Number:
- MFCD00672498
- MOL File:
- 117946-91-5.mol
- MSDS File:
- SDS
| Melting point | 44-46°C |
|---|---|
| Boiling point | 434.31°C (rough estimate) |
| Density | 1.1045 (rough estimate) |
| refractive index | 1.6140 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: 5 mg/mL |
| form | White to off-white crystalline solid. |
| pka | 16.36±0.46(Predicted) |
| color | Off-White to Yellow |
| Water Solubility | Soluble in DMSO (100 mM), ethanol (100 mM), chloroform, methanol, and water. |
| Stability | Store at -20°C |
| CAS DataBase Reference | 117946-91-5(CAS DataBase Reference) |
| FDA UNII | B31Y10A9UR |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| RTECS | AC7765700 |
| HS Code | 29339980 |
LUZINDOLE price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | L2407 | Luzindole ≥90% | 117946-91-5 | 5mg | $179 | 2024-03-01 | Buy |
| TCI Chemical | L0316 | Luzindole >98.0%(HPLC) | 117946-91-5 | 25mg | $300 | 2024-03-01 | Buy |
| Alfa Aesar | J61915 | Luzindole, 97% | 117946-91-5 | 5mg | $125.65 | 2024-03-01 | Buy |
| Alfa Aesar | J61915 | Luzindole, 97% | 117946-91-5 | 25mg | $453 | 2021-12-16 | Buy |
| Cayman Chemical | 15998 | Luzindole ≥98% | 117946-91-5 | 5mg | $62 | 2024-03-01 | Buy |
LUZINDOLE Chemical Properties,Uses,Production
Chemical Properties
Off-White Amorphous Solid
Uses
A melatonin receptor antagonist
Uses
Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response
Definition
ChEBI: A member of the class of indoles that is tryptamine in which one of the amino hydrogens is replaced by an acetyl group while the hydrogen at position 2 is replaced by a benzyl group.
Biological Activity
Melatonin antagonist.
Biochem/physiol Actions
Luzindole is a melatonin (mel) receptor antagonist. It has higher affinity towards the Mel 1b receptor than the Mel 1a receptor subtype.
storage
Store at -20°C
LUZINDOLE Preparation Products And Raw materials
Raw materials
Preparation Products
LUZINDOLE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32222 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5899 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 12272 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
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