ChemicalBook >> CAS DataBase List >>5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide

5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide

CAS No.
1252927-47-1
Chemical Name:
5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide
Synonyms
GSK-1071306;N-Demethyl Pazopanib;Pazopanib Impurity 13;Pazopanib Impurity 41;Pazopanib impurity 02;Pazopanib Impurity 56;Pazopanib metabolite M27;Pazopanib metabolite M27 HCl;Pazopanib N-Desmethyl Impurity;Pazopanib metabolite M27 Hydrochloride
CBNumber:
CB62695422
Molecular Formula:
C20H21N7O2S
Molecular Weight:
423.49144
MDL Number:
MFCD28130076
MOL File:
1252927-47-1.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide Properties

Melting point >252°C (dec.)
storage temp. Refrigerator
solubility DMSO (Slightly), Ethyl Acetate (Slightly)
form Solid
color Pale Yellow
FDA UNII Z51V93OIDV

5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D474025 N-DemethylPazopanib 1252927-47-1 50mg $845 2021-12-16 Buy
Product number Packaging Price Buy
D474025 50mg $845 Buy

5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide Chemical Properties,Uses,Production

Uses

N-demethyl Pazopanib is a Pazopanib (P210925) impurity. Pazopanib is an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

Uses

5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)amino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide is a Pazopanib (P210925) impurity. Pazopanib is an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44808 58
GSK-1071306 5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide Pazopanib Impurity 13 N-Demethyl Pazopanib Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)amino]-2-pyrimidinyl]amino]-2-methyl- Pazopanib N-Desmethyl Impurity Pazopanib Impurity 41 5-[[4-[(2,3-dimethylindazol-6-yl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide Pazopanib metabolite M27 HCl Pazopanib metabolite M27 Pazopanib metabolite M27 Hydrochloride Pazopanib impurity 02 Pazopanib Impurity 56 1252927-47-1 Metabolites & Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals