MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl
- CAS No.
- 856307-27-2
- Chemical Name:
- MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl
- Synonyms
- Metamizole EP Impurity C;Metamizole EP Impurity C HCl;4-Methylamino-1,5-dimethyl-2-phenyl;4-Methylaminophenazone Hydrochloride;4-Methylaminoantipyrine hydrochloride;Metamizole EP Impurity C Hydrochloride;N-Methyl-4-aminoantipyrine Hydrochloride;Antipyrine,4-(methylamino)-, hydrochloride;MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl;Metamizole Sodium Monohydrate EP Impurity C as Hydrochloride
- CBNumber:
- CB62706986
- Molecular Formula:
- C12H16ClN3O
- Molecular Weight:
- 253.73
- MDL Number:
- MFCD16620361
- MOL File:
- 856307-27-2.mol
SAFETY
Risk and Safety Statements
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MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-0114022 | 4-Methylaminoantipyrine(hydrochloride) | 856307-27-2 | 25mg | $105 | 2021-12-16 | Buy |
ChemScene | CS-0114022 | 4-Methylaminoantipyrine(hydrochloride) | 856307-27-2 | 50mg | $155 | 2021-12-16 | Buy |
ChemScene | CS-0114022 | 4-Methylaminoantipyrine(hydrochloride) | 856307-27-2 | 100mg | $245 | 2021-12-16 | Buy |
MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl Chemical Properties,Uses,Production
Uses
4-Methylaminoantipyrine Hydrochloride is a useful research chemical, a methylamino antipyrine derivatives.
Biological Activity
4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. It has analgesic, antipyretic and relatively weak anti-inflammatory properties.
in vitro
Metamizole is a prodrug which, at room temperature and in an atmosphere with oxygen, is spontaneously, nonenzymatically converted to 4-Methylamino antipyrine. Subsequently, the N-methyl side chain of 4-Methylamino antipyrine is oxidized to yield 4-formylaminoantipyrine, which is further converted to 4-aminoantipyrine. Metamizole in aqueous solution and in the presence of oxygen consists of a group of several pyrazolone derivatives of which 4-Methylamino antipyrine is pharmacologically the most important.
in vivo
The aim of this study is to assess the pharmacokinetics of its active metabolites 4-Methylamino antipyrine in male piglets after a single intramuscular injection of Metamizole. Eight healthy male piglets are administered Metamizole (100 mg/kg) intramuscularly. 4-Methylamino antipyrine plasma concentrations are quantitatively detectable from 0.25 to 48 h. The average maximum concentration of it is of 47.59 mg/mL. The average half-lives is 8.57 h for 4-Methylamino antipyrine.
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MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl Preparation Products And Raw materials
Raw materials
Preparation Products
MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl Suppliers
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TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
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