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Centrinone-B

Centrinone-B Structure
Centrinone-B structure
CAS No.
1798871-31-4
Chemical Name:
Centrinone-B
Synonyms
LCR-323;Centrinone-B;Centrinone B,CentrinoneB;2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(piperidin-1-yl)pyrimidin-4-amine;2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-4-pyrimidinamine;4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-
CBNumber:
CB63067004
Molecular Formula:
C27H27F2N7O5S2
Molecular Weight:
631.67
MDL Number:
MFCD29472297
MOL File:
1798871-31-4.mol
Last updated:2023-06-30 15:45:59
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Centrinone-B Properties

Boiling point 904.9±75.0 °C(Predicted)
Density 1.54±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 8.5 mg/mL (13.46 mM)
pka 13.68±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

Centrinone-B price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 5690 CentrinoneB ≥98%(HPLC) 1798871-31-4 10 $259 2021-12-16 Buy
TRC C256610 Centrinone-B 1798871-31-4 5mg $500 2021-12-16 Buy
TRC C256610 Centrinone-B 1798871-31-4 10mg $1495 2021-12-16 Buy
TRC C256610 Centrinone-B 1798871-31-4 1mg $130 2021-12-16 Buy
ChemScene CS-5374 Centrinone-B 98.97% 1798871-31-4 5mg $144 2021-12-16 Buy
Product number Packaging Price Buy
5690 10 $259 Buy
C256610 5mg $500 Buy
C256610 10mg $1495 Buy
C256610 1mg $130 Buy
CS-5374 5mg $144 Buy

Centrinone-B Chemical Properties,Uses,Production

Uses

Centrinone-B is a high affinity and selective PLK4 inhibitor. It depletes centriole and centrosome levels in vitro and induces cell cycle arrest in normal human cell lines in a p53-dependent manner.

storage

Store at -20°C

Centrinone-B Preparation Products And Raw materials

Raw materials

Preparation Products

Centrinone-B Suppliers

Global( 27)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3429 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7892 56
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29795 68
Musechem +1-800-259-7612 info@musechem.com United States 4662 60
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Haoyuan Chemexpress Co., Ltd. 61
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Beijing Solarbio Science & Tecnology Co., Ltd. 68
Musechem 60
BOC Sciences 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Centrinone-B 2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-4-pyrimidinamine LCR-323 4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)- Centrinone B,CentrinoneB 2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(piperidin-1-yl)pyrimidin-4-amine 1798871-31-4 C27H27F2N7O5S2