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ChemicalBook >> CAS DataBase List >> Centrinone-B

Centrinone-B

Centrinone-B price.
  • $101 - $1495
  • Product name: Centrinone-B
  • CAS: 1798871-31-4
  • MF: C27H27F2N7O5S2
  • MW: 631.67
  • EINECS:
  • MDL Number:MFCD29472297
  • Synonyms:Centrinone-B;2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-4-pyrimidinamine;LCR-323;4-Pyrimidinamine, 2-[[2-fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-;Centrinone B,CentrinoneB;2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(piperidin-1-yl)pyrimidin-4-amine
Price10 Properties Safety Information Description
10 prices
Selected condition：
Brand
  • ChemScene
  • Crysdot
  • Tocris
  • TRC
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerChemScene
  • Product numberCS-5374
  • Product descriptionCentrinone-B 98.97%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5374
  • Product descriptionCentrinone-B 98.97%
  • Packaging10mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5374
  • Product descriptionCentrinone-B 98.97%
  • Packaging50mg
  • Price$1080
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002919
  • Product descriptionCentrinone-B 98+%
  • Packaging5mg
  • Price$101
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002919
  • Product descriptionCentrinone-B 98+%
  • Packaging10mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002919
  • Product descriptionCentrinone-B 98+%
  • Packaging50mg
  • Price$686
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number5690
  • Product descriptionCentrinoneB ≥98%(HPLC)
  • Packaging10
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC256610
  • Product descriptionCentrinone-B
  • Packaging1mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC256610
  • Product descriptionCentrinone-B
  • Packaging5mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC256610
  • Product descriptionCentrinone-B
  • Packaging10mg
  • Price$1495
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ChemScene CS-5374 Centrinone-B 98.97% 5mg $144 2021-12-16 Buy
ChemScene CS-5374 Centrinone-B 98.97% 10mg $240 2021-12-16 Buy
ChemScene CS-5374 Centrinone-B 98.97% 50mg $1080 2021-12-16 Buy
Crysdot CD31002919 Centrinone-B 98+% 5mg $101 2021-12-16 Buy
Crysdot CD31002919 Centrinone-B 98+% 10mg $166 2021-12-16 Buy
Crysdot CD31002919 Centrinone-B 98+% 50mg $686 2021-12-16 Buy
Tocris 5690 CentrinoneB ≥98%(HPLC) 10 $259 2021-12-16 Buy
TRC C256610 Centrinone-B 1mg $130 2021-12-16 Buy
TRC C256610 Centrinone-B 5mg $500 2021-12-16 Buy
TRC C256610 Centrinone-B 10mg $1495 2021-12-16 Buy

Properties

Boiling point :904.9±75.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 8.5 mg/mL (13.46 mM)
form :Solid
pka :13.68±0.10(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Centrinone-B is a high affinity and selective PLK4 inhibitor. It depletes centriole and centrosome levels in vitro and induces cell cycle arrest in normal human cell lines in a p53-dependent manner.

Suppliers and manufacturers

TargetMol Chemicals Inc.
Aladdin Scientific
Amadis Chemical Company Limited Haoyuan Chemexpress Co., Ltd. ShangHai Caerulum Pharma Discovery Co., Ltd. Sichuan Wei Keqi Biological Technology Co., Ltd. Beijing Solarbio Science & Tecnology Co., Ltd. Musechem BOC Sciences ChemeGen(Shanghai) Biotechnology Co.,Ltd.