N6-benzoyl-Cyclic AMP (sodium salt)
- CAS No.
- 1135306-29-4
- Chemical Name:
- N6-benzoyl-Cyclic AMP (sodium salt)
- Synonyms
- N6-benzoyl-Cyclic AMP (sodium salt);6BnzcAMP sodium salt,6 Bnz cAMP sodium salt
- CBNumber:
- CB63152696
- Molecular Formula:
- C17H15N5NaO7P
- Molecular Weight:
- 457.31
- MDL Number:
- MFCD01074967
- MOL File:
- 1135306-29-4.mol
N6-benzoyl-Cyclic AMP (sodium salt) price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 18819 | N6-benzoyl-Cyclic AMP (sodium salt) ≥98% | 1135306-29-4 | 5mg | $238 | 2024-03-01 | Buy |
| Cayman Chemical | 18819 | N6-benzoyl-Cyclic AMP (sodium salt) ≥98% | 1135306-29-4 | 10mg | $452 | 2024-03-01 | Buy |
| TRC | A281758 | N6-Benzoyladenosine3’,5’-CyclicMonophosphateSodiumSalt | 1135306-29-4 | 0.5mg | $80 | 2021-12-16 | Buy |
| TRC | A281758 | N6-Benzoyladenosine3’,5’-CyclicMonophosphateSodiumSalt | 1135306-29-4 | 2.5mg | $200 | 2021-12-16 | Buy |
| ApexBio Technology | B7791 | 6-Bnz-cAMP sodium salt | 1135306-29-4 | 5mg | $257 | 2021-12-16 | Buy |
N6-benzoyl-Cyclic AMP (sodium salt) Chemical Properties,Uses,Production
Description
N6-benzoyl-Cyclic AMP (6-Bnz-cAMP) is a cell permeable cAMP analog that selectively activates PKA over exchange proteins activated by cAMP (Epac1 and 2, also known as RAPGEF3 and 4). It binds the AI and AII subunits of PKA with pKi values of 4.0 and 3.8, respectively, whereas it binds Epac1 with a pKi value of 1.3. 6-Bnz-cAMP stimulates the phosphorylation of the PKA substrate CREB but does not activate the Epac target Rap1. It can act synergistically with Epac-selective activators, such as 8-pCPT-2’-O-Me-cAMP .
Uses
N6-Benzoyladenosine 3’,5’-Cyclic Monophosphate Sodium Salt is a potent, cell-permeable PKA activator.
storage
Store at -20°C
References
[1]lo kw, kan hm, ashe km, laurencin ct. the small molecule pka-specific cyclic amp analogue as an inducer of osteoblast-like cells differentiation and mineralization. j tissue eng regen med. 2012 jan;6(1):40-8.
[2]simone kiermayer, ricardo m. biondi,etal., epac activation converts camp from a proliferative into a differentiation signal in pc12 cells. molecular biology of the cell. vol. 16, 5639–5648, december 2005.
[3]cheng x, ji z, tsalkova t, mei f. epac and pka: a tale of two intracellular camp receptors. acta biochim biophys sin (shanghai). 2008 jul;40(7):651-62.
N6-benzoyl-Cyclic AMP (sodium salt) Preparation Products And Raw materials
Raw materials
Preparation Products
N6-benzoyl-Cyclic AMP (sodium salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32080 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52925 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11217 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Guangzhou Yunmen Biotechnology Co., Ltd | 18902340307 18902340307 | 3356812514@qq.com | China | 9245 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4870 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |