N6-benzoyl-Cyclic AMP (sodium salt)

N6-benzoyl-Cyclic AMP (sodium salt) 구조식 이미지
카스 번호:
1135306-29-4
상품명:
N6-benzoyl-Cyclic AMP (sodium salt)
동의어(영문):
N6-benzoyl-Cyclic AMP (sodium salt);6BnzcAMP sodium salt,6 Bnz cAMP sodium salt
CBNumber:
CB63152696
분자식:
C17H15N5NaO7P
포뮬러 무게:
457.31
MOL 파일:
1135306-29-4.mol

N6-benzoyl-Cyclic AMP (sodium salt) 속성

저장 조건
Store at -20°C
용해도
Soluble in H2O
물리적 상태
결정질 고체
색상
White to off-white
수용성
물에 100mM까지 용해됨

안전

N6-benzoyl-Cyclic AMP (sodium salt) C화학적 특성, 용도, 생산

개요

N6-benzoyl-Cyclic AMP (6-Bnz-cAMP) is a cell permeable cAMP analog that selectively activates PKA over exchange proteins activated by cAMP (Epac1 and 2, also known as RAPGEF3 and 4). It binds the AI and AII subunits of PKA with pKi values of 4.0 and 3.8, respectively, whereas it binds Epac1 with a pKi value of 1.3. 6-Bnz-cAMP stimulates the phosphorylation of the PKA substrate CREB but does not activate the Epac target Rap1. It can act synergistically with Epac-selective activators, such as 8-pCPT-2’-O-Me-cAMP .

N6-benzoyl-Cyclic AMP (sodium salt) 준비 용품 및 원자재

원자재

준비 용품


N6-benzoyl-Cyclic AMP (sodium salt) 공급 업체

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