ChemicalBook >> CAS DataBase List >>(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- CAS No.
- 125971-94-0
- Chemical Name:
- (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
- Synonyms
- ATS-8;(4R,CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R-CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-8);tert-Butyl 2-((4R,6R)-6-(cyanoMethyl)-2,2-diMethyl-1,3-dioxan-4-yl)acetate;(4R,6R)-tert-Butyl-6;Atorvastatin Impurity 7;Atorvastatin calcium-11;Ats-8(For Atorvastatin);Atorvastatin Impurity 63;(4R,6R)-Tert-Butyl-6-Cyanometh
- CBNumber:
- CB6327897
- Molecular Formula:
- C14H23NO4
- Molecular Weight:
- 269.34
- MDL Number:
- MFCD03093958
- MOL File:
- 125971-94-0.mol
- MSDS File:
- SDS
Last updated:2024-11-21 18:03:03
| Melting point | 65-69 °C(lit.) |
|---|---|
| Boiling point | 364.1±17.0 °C(Predicted) |
| Density | 1.016±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform |
| form | powder to crystal |
| color | White to Almost white |
| optical activity | [α]20/D 1.0°, c = 1 in chloroform |
| CAS DataBase Reference | 125971-94-0(CAS DataBase Reference) |
| FDA UNII | UW4BC1SFB0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 539015 | tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 97% | 125971-94-0 | 1g | $48.4 | 2024-03-01 | Buy |
| TCI Chemical | B3642 | tert-Butyl (4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate >98.0%(GC)(N) | 125971-94-0 | 5g | $85 | 2024-03-01 | Buy |
| TRC | C982020 | (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-aceticAcid1,1-DimethylethylEster | 125971-94-0 | 500mg | $110 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CCH0000262 | (4R -CIS)-1, 1-DIMETHYLETHYL -6- CYANOMETHYL-2, 2-DIMETHYL-1, 3-DIOXANE-4-ACETATE 95.00% | 125971-94-0 | 1G | $123.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB32752 | (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate | 125971-94-0 | 25g | $400 | 2021-12-16 | Buy |
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester is an intermediate of Atorvastatin (A791750, Ca salt), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
Uses
Atorvastatin Intermediate
Synthesis of (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate from sodium:cyanide and (4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 361)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Yutian pharmaceutical Co.,Ltd. | +undefined-0518-86098006 +undefined19851887368 | lvan.hui@jsytsw.com | China | 80 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 998 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 970 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18777 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2963 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
View Lastest Price from (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-26 | (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
125971-94-0
|
US $80.00 / kg | 1kg | 99% | 5000 | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-11-22 | (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
125971-94-0
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-21 | (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
125971-94-0
|
US $786.00 / Kg | 0.100Kg | 99 % | 5000 Kg | R&D Scientific Inc. |
-
- (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
125971-94-0
- US $80.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
-
- (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
125971-94-0
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
125971-94-0
- US $786.00 / Kg
- 99 %
- R&D Scientific Inc.
125971-94-0((4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate)Related Search:
(4R,6R)-T-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
(4R,6R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
(4R,3R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
tert-Butyl (4R,3R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXAN-4-YL]ACETATE
(4R,6R)-t-butyl-6-cyanomethyl02,2-dimethyl-1,3-dioxane-4-acetate
(4R-cis)-1,1-dimethylethyl-6-cyanomethyl -2,2-dimethyl-1,3-dloxane-4-acetate
(4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
1,3-Dioxane-4-aceticacid, 6-(cyanoMethyl)-2,2-diMethyl-, 1,1-diMethylethyl ester, (4R,6R)-
tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate 97%
tert-Butyl (4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Atorvastatin intermediatesAts-8
(4R-Cis)-l,l-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Aceta
Ats-8:(4R,Cis)-1,1-Dimethylethyl-Cyanomethyl-2,2-Dimethyl
(4R)-cis-6-1,1-Dimethyl-6-cyanomethyl-2-2-dimethyl-1,3-dioaneacetate
Intermediateofatorvastatinecalcium(CAS#134523-03-8)
1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-1,1-dimethylethylester
TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-1,3-DIOXAN-4-YL]ACETATE
(4R,6R)-t-Butyl-6-AMINOMETHYL-2,2-dimethyl-1,3-dioxane-4-acetate
(4R,6R)-Tert-Butyl-6-Cyanometh
ATS 8 (4R,CIS)-1,1-DIMETHYLETHY-L-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
ATS-8:(4R-CIS)-T-ETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,2-DIMETHYL-1,2-DIONMANO 1 ACETATE
(4R-Cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dio-cxane-4-acetate
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate,97%
Tert-Butyl(3R,5R)-6-cyano-3,5-O-iso-propylidene-3,5-dihydroxyhexanoate
(4R,6R)-tert-Butyl-6
(4R-Cis)-1,1-diMethylethyl-6-Cyanoethyl-2,2-diMethyl-1,3-dioxane-4-acetate
ATS-8 (4R, cis)C1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane C4-Acetate
Tetr-butyl[(4R,6R)-6-cyanomethyl-1,3-dioxan-4-yl]acetate
tert-Butyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxolane-4-acetate
tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
2-[6-(cyanoMethyl)-2,2-diMethyl-1,3-dioxan-4-yl]-3,3-diMethylbutanoate
Atorvastatin Impurity 7
Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6R)-Isomer
4R CIS)-1.1-DIMETHYLETHYL-6-CYANOMETHYL- 2 2-DIMETHYL-1 3-DIOXANE-4-ACETAT
Atorvastatin Impurity 63
2-[6-(bromomethyl)-1,3-dioxan-4-yl]-3,3-dimethylbutanoate
Atorvastatin Calcium Hydrate impurity 19
Atorvastatin calcium-11
Ats-8(For Atorvastatin)
((4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-[1,3]dioxan-4-yl)acetic acid tert-butyl ester
tert-Butyl(4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate>
(4R,6R)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-
4-acetate(A8)
(4R-cis)-6-1,1-Dimethyl-6-cyanomethly-2-2-dimethly-1,3-dioane-acetate
(4r-Cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Di...
ATS-8
(4R,CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
(4R-CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-8)
tert-Butyl 2-((4R,6R)-6-(cyanoMethyl)-2,2-diMethyl-1,3-dioxan-4-yl)acetate
tert-Butyl 2-((4R,6R)-6-cyanomethyl-2,2- dimethyl-1,3-dioxane-4-yl)acetate
1,1-Dimethylethyl (4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
(4r,6r)-tert-butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate (ATS-8)
Atorvastatin calcium impurity 19
(4R,Cis)-1,1-dimethylethyl-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate (ATS-8)
ATS-8（Intermediate of Atorvastatin)
125971-94-0
129571-94-0