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SMI-16a

SMI-16a Structure
SMI-16a structure
CAS No.
587852-28-6
Chemical Name:
SMI-16a
Synonyms
SMI-16a;SMI-16A;SMI 16A;SMI16A;PIM1/2 Kinase Inhibitor VI;SMI-16a(PIM1/2 Kinase Inhibitor VI);5-(4-propoxybenzylidene)thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-;SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases
CBNumber:
CB63313558
Molecular Formula:
C13H13NO3S
Molecular Weight:
263.31
MDL Number:
MFCD31382191
MOL File:
587852-28-6.mol
Last updated:2024-07-02 08:55:14
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SMI-16a Properties

Melting point 186.3-188.4 °C
Density 1.303±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
form A solid
pka 7.27±0.20(Predicted)
color Light yellow to yellow

SMI-16a price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29456 SMI-16a 587852-28-6 5mg $93 2024-03-01 Buy
Cayman Chemical 29456 SMI-16a 587852-28-6 25mg $365 2024-03-01 Buy
Cayman Chemical 29456 SMI-16a 587852-28-6 10mg $166 2024-03-01 Buy
ChemScene CS-6913 SMI-16a 99.70% 587852-28-6 10mg $216 2021-12-16 Buy
ChemScene CS-6913 SMI-16a 99.70% 587852-28-6 5mg $120 2021-12-16 Buy
Product number Packaging Price Buy
29456 5mg $93 Buy
29456 25mg $365 Buy
29456 10mg $166 Buy
CS-6913 10mg $216 Buy
CS-6913 5mg $120 Buy

SMI-16a Chemical Properties,Uses,Production

Description

SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM). It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 μM) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.

SMI-16a Preparation Products And Raw materials

Raw materials

Preparation Products

SMI-16a Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38632 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66099280 17798518460 cfzhang@aikonchem.com China 19915 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 27313 60
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60

View Lastest Price from SMI-16a manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SMI-16a pictures 2019-12-24 SMI-16a
587852-28-6
 US $1.00 / g 1g 99% 20kg Career Henan Chemical Co
  • SMI-16a pictures
  • SMI-16a
    587852-28-6
  • US $1.00 / g
  • 99%
  • Career Henan Chemical Co
SMI-16a PIM1/2 Kinase Inhibitor VI SMI-16a(PIM1/2 Kinase Inhibitor VI) SMI-16A;SMI 16A;SMI16A 2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]- SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases 5-(4-propoxybenzylidene)thiazolidine-2,4-dione 587852-28-6