Wogonin
- CAS No.
- 632-85-9
- Chemical Name:
- Wogonin
- Synonyms
- 5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-on;5,7-DIHYDROXY-8-METHOXYFLAVON;5,7-DIHYDROXY-8-METHOXYFLAVONE;5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-one;WOGONIN;vogonin;WOOGONIN;WILDYAMP.E;WOGONIN(RG);WOGONIN hplc
- CBNumber:
- CB6408918
- Molecular Formula:
- C16H12O5
- Molecular Weight:
- 284.26
- MDL Number:
- MFCD00017736
- MOL File:
- 632-85-9.mol
- MSDS File:
- SDS
Melting point | 203-206°C |
---|---|
Boiling point | 518.8±50.0 °C(Predicted) |
Density | 1.420±0.06 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
solubility | DMSO: ≥20mg/mL |
pka | 6.83±0.40(Predicted) |
form | Yellow solid |
color | Light Yellow to Yellow |
λmax | 319nm(EtOH)(lit.) |
InChIKey | XLTFNNCXVBYBSX-UHFFFAOYSA-N |
LogP | 2.140 (est) |
CAS DataBase Reference | 632-85-9(CAS DataBase Reference) |
FDA UNII | POK93PO28W |
SAFETY
Risk and Safety Statements
Safety Statements | 24/25 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
WGK Germany | 3 | |||||||||
RTECS | LK8331000 | |||||||||
HS Code | 29329990 | |||||||||
NFPA 704 |
|
Wogonin price More Price(49)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | W0769 | Wogonin hydrate ≥98% (HPLC), solid | 632-85-9 | 5mg | $220 | 2024-03-01 | Buy |
Sigma-Aldrich | 681670 | Wogonin hydrate | 632-85-9 | 10mg | $273 | 2023-01-07 | Buy |
TCI Chemical | W0010 | Wogonin >98.0%(HPLC) | 632-85-9 | 50mg | $140 | 2024-03-01 | Buy |
TCI Chemical | W0010 | Wogonin >98.0%(HPLC) | 632-85-9 | 250mg | $418 | 2024-03-01 | Buy |
Cayman Chemical | 14248 | Wogonin ≥98% | 632-85-9 | 5mg | $64 | 2024-03-01 | Buy |
Wogonin Chemical Properties,Uses,Production
Uses
Wogonin acts as an anti-inflammatory agent, attenuating ovalbumin antigen-influenced neutrophillic airway inflammation. In addition, it reverses multi-drug resistance of human myelogenous leukemia.
Definition
ChEBI: A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8.
General Description
Wogonin is a flavonoid component of Scutellaria baicalensis Georgi roots.
Biochem/physiol Actions
Wogonin is an anti-inflammatory agent and COX-2 inhibitor, which inhibits the induction of both iNOS and COX-2. Wogonin inhibits COX-2 (IC50 = 46 μM) without affecting COX-1. Wogonin inhibits iNOS induction and thus inhibts activation-induced C6 glial cell death. Specifically, Wogonin inhibits NF-kappaB-mediated iNOS induction.
storage
Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Wogonin Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shandong Natural Micron Pharm Tech Co.,LTD | +86-18653895227 | info@nmpharmtech.com | China | 94 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 2990 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5895 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 346 | 58 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9284 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
View Lastest Price from Wogonin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-29 | Wogonin
632-85-9
|
US $10.50 / KG | 1KG | 98% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-05-23 | Wogonin
632-85-9
|
US $0.00-0.00 / kg | 1kg | 0.99 | 500000kg | Hebei Kingfiner Technology Development Co.Ltd | ||
2024-04-22 | Wogonin
632-85-9
|
US $0.00 / kg | 1kg | 99.8% | 1000 kg | BINBO BIOLOGICAL CO.,LTD |