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Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

CAS No.
128625-52-5
Chemical Name:
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
Synonyms
PYBOP;BOPP;BOP REAGENT;((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphoniuM hexafluorophosphate(V);(BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;BENZOTRIAZOLE-1-YL-OXY-TRIS-PYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE;1H-BENZOTRIAZOL-1-YLOXYTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;[(1H-Benzotriazol-1-yl)oxy][tri(pyrrolidin-1-yl)]phosphonium hexafluorophosphate;BYPOP;PYBOP(R)
CBNumber:
CB6434717
Molecular Formula:
C18H28F6N6OP2
Molecular Weight:
520.39
MDL Number:
MFCD00077411
MOL File:
128625-52-5.mol
MSDS File:
SDS
Last updated:2024-10-29 11:48:24

Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Properties

Melting point 154-156 °C (dec.)(lit.)
Density 1.438 at 20℃
vapor pressure 0-0Pa at 20-50℃
storage temp. 2-8°C
solubility methanol: 25 mg/mL, clear
form Fine Crystalline Powder
color White to off-white
Sensitive Moisture Sensitive
BRN 3584612
InChI InChI=1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1
InChIKey BYCLGHOAELJLOF-UHFFFAOYSA-M
SMILES [P+](ON1N=NC2C=CC=CC1=2)(N1CCCC1)(N1CCCC1)N1CCCC1.[P-](F)(F)(F)(F)(F)F
LogP -0.3 at 26℃ and pH3.5-3.7
CAS DataBase Reference 128625-52-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H317-H410
Precautionary statements  P261-P264-P273-P280-P301+P312-P302+P352
Hazard Codes  Xi
Risk Statements  37/38-44-36/37/38
Safety Statements  26-36-24/25-37/39
RIDADR  UN 1325 4.1/PG 2
WGK Germany  3
8-10-21
Hazard Note  Irritant
HS Code  29339980
NFPA 704
1
2 0

Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.51009 PyBOP Novabiochem? 128625-52-5 25g $123 2024-03-01 Buy
Sigma-Aldrich 8.51009 PyBOP Novabiochem? 128625-52-5 100g $367 2024-03-01 Buy
Sigma-Aldrich 12805 (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate purum, ≥97.0% (TLC) 128625-52-5 1g $81.9 2024-03-01 Buy
Sigma-Aldrich 12805 (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate purum, ≥97.0% (TLC) 128625-52-5 5G $96 2024-03-01 Buy
Sigma-Aldrich 12805 (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate purum, ≥97.0% (TLC) 128625-52-5 25g $298 2024-03-01 Buy
Product number Packaging Price Buy
8.51009 25g $123 Buy
8.51009 100g $367 Buy
12805 1g $81.9 Buy
12805 5G $96 Buy
12805 25g $298 Buy

Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl) phosphonium hexafluorophosphate is a peptide coupling reagent utilized in solid phase peptide synthesis. It is also used as a substitute for the (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.

Uses

One of the most convenient coupling reagents for peptide synthesis without carcinogenic by-products. It replaces BOP reagent. This is especially suitable for solid-phase peptide synthesis, avoids racemization.

Uses

Reagent for:
Synthesis of single labeled oligonucleotides that fluoresce upon matched hybridization
Generation of endocrine disruptor chemical binders
Cycloaddition to template-assembled multivalent peptide conjugates

General Description

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification. It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.

Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 547)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangsu Vcan Advanced Material Co., Ltd.
+86-17306299870 +86-18652789875 vcanam@vcanam.com China 32 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12837 58
Watson Biotechnology Co.,Ltd
+86-18186686046 +86-18186686046 sales01@watsonbiotech.cn China 5822 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18648 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21639 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3009 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32820 60
AB PharmaTech,LLC
323-480-4688 sales@acrospharmatech.com United States 989 55

View Lastest Price from Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate pictures 2024-11-02 Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
128625-52-5
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
PyBOP Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate pictures 2024-11-02 PyBOP Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
128625-52-5
US $0.00-0.00 / kg 1kg 99% 20MT Watson Biotechnology Co.,Ltd
PyBOP pictures 2024-10-17 PyBOP
128625-52-5
US $0.00 / KG 1KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd
  • PyBOP pictures
  • PyBOP
    128625-52-5
  • US $0.00 / KG
  • 99%
  • Hebei Weibang Biotechnology Co., Ltd
pybop?/td> BENZOTRIAZOLYL-N-OXYTRIS-(DIMETHYLAMINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE) BENZOTRIAZOL-1-YL-OXYTRIPYRROLIDINPHOSPHONIUM HEXAFLUOROPHOSPHATE Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate BENZOTRIAZOLE-1-YL-OXY-TRIS-DIMETHYLAMINOPHOPHONIUM BENZOTRIAZOL-1-YLOXYTRIS(PYRROLIDINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOPHONIUM HEXAFLUOROPHOSPHATE BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM BENZOTRIAZOLE-1-YL-OXY-TRIS-(DIMETHYLAMINO)-PHOSPHONIUM HEXAFLUOROPHOSPHATE BENZOTRIAZOLE-1-YL-OXY-TRIS-PYRRORIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE HEXAFLUOROPHOSPHATE BOP CASTROS REAGENT CASTRO'S REAGENT PYBOP(R) Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluoroph Benzotriazol-1-yloxytri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 98% PYBOP(R),99% (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate,PyBOP Benzotriazol-1-yl-ox (Benzotriazol-1-yloxy)tripyrrolidinophosphonium he 1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 98% PyBOP (OR) Benzotriazol-1-yloxy tripyrrolidinophosphoniuM hexafluorophosphate PYBOP, 99% 5GR (1H-Benzotriazol-1-yloxy)(diMethylaMino)di(pyrrolidin-1-yl)phosphoniuM Phosphorus(1+),[1-(hydroxy-kO)-1H-benzotriazolato]tri-1-pyrrolidinyl-,(T-4)-, hexafluorophosphate(1-) (1:1) BENZOTRIAZOL-1-YL-OXYTRIPYRROLIDINO-PHOS PHONIUM (BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM F6 PHOSPHATE PYBOP [BENZOTRIAZOL-1-YLOXYTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE] Benzotriazol-1-yloxytris(pyrrolidino)phosphoniumh Benzotriazol-1-yloxytris-(pyrrolidino)-phosphonium Benzotriazol-1-yloxytripyrroli Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphateBenzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Benzotriazol-1-yloxytris(pyrrolidino)phosphonium Hexafluorophosphate (PyBOP) Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphat PYBOP ((1H-BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUMHEXAFLUOROPHOSPHATE) Benzotriazole-1-ly-oxy-tris-pyrrolidinophosphonium hexafluorphosphate 1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate [Coupling Reagent for Peptide] Benzotriazol-1-yl-oxytrispyrrolidinophosphonium hexafluorophosphate, 97+% Benzotriazole-1-yl-oxy-trispyrrolidinophosphonium hexafluorophosphate ,99% (Benzotriazol-1-yloxy)tripyrrolidinophosphoniuM hexafluorophosphate 98% 1H-Benzotriazol-1-yloxytripyrrolidinophosphoniuM hexafluorophosphate, 98.0%(LC) 1 h benzotriazole - 1 - three pyrrole alkyl six fluoride phosphate PyBOP base oxygen enzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate≥ 99% (HPLC) PyBOP Novabiochem 1-Benzotriazolyloxytripyrrolidinylphosphonium hexafluorophosphate (1H-1,2,3-benzotriazol-1-yloxy)tris(pyrrolidin-1-yl)phosphanium Unable to generate chemical name BENZOTRIAZOLYL-N-OXYTRIS-(DIMETHY Benzotriazol-1-yloxytrispyrrolidinophosphonium hexafluorophosphate, 99%, for synthesis 1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate [Coupling Reagent for Peptide]> PYBOP 25 G PYBOP 100 G idinophosphonium hexafL oxytripyrroL Phosphorus(1+), [1-(hydroxy-κO)-1H-benzotriazolato]tri-1-pyrrolidinyl-, (T-4)-, hexafluorophosphate(1-) (1:1) PyBOP, 99% min. Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate USP/EP/BP