Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
- CAS No.
- 128625-52-5
- Chemical Name:
- Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
- Synonyms
- PYBOP;BOPP;BOP REAGENT;((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphoniuM hexafluorophosphate(V);(BENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;BENZOTRIAZOLE-1-YL-OXY-TRIS-PYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE;1H-BENZOTRIAZOL-1-YLOXYTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;[(1H-Benzotriazol-1-yl)oxy][tri(pyrrolidin-1-yl)]phosphonium hexafluorophosphate;BYPOP;PYBOP(R)
- CBNumber:
- CB6434717
- Molecular Formula:
- C18H28F6N6OP2
- Molecular Weight:
- 520.39
- MDL Number:
- MFCD00077411
- MOL File:
- 128625-52-5.mol
- MSDS File:
- SDS
Melting point | 154-156 °C (dec.)(lit.) |
---|---|
Density | 1.438 at 20℃ |
vapor pressure | 0-0Pa at 20-50℃ |
storage temp. | 2-8°C |
solubility | methanol: 25 mg/mL, clear |
form | Fine Crystalline Powder |
color | White to off-white |
Sensitive | Moisture Sensitive |
BRN | 3584612 |
InChI | InChI=1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1 |
InChIKey | BYCLGHOAELJLOF-UHFFFAOYSA-M |
SMILES | [P+](ON1N=NC2C=CC=CC1=2)(N1CCCC1)(N1CCCC1)N1CCCC1.[P-](F)(F)(F)(F)(F)F |
LogP | -0.3 at 26℃ and pH3.5-3.7 |
CAS DataBase Reference | 128625-52-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS09 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H317-H410 | |||||||||
Precautionary statements | P261-P264-P273-P280-P301+P312-P302+P352 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 37/38-44-36/37/38 | |||||||||
Safety Statements | 26-36-24/25-37/39 | |||||||||
RIDADR | UN 1325 4.1/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 8-10-21 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29339980 | |||||||||
NFPA 704 |
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Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate price More Price(56)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.51009 | PyBOP Novabiochem? | 128625-52-5 | 25g | $123 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.51009 | PyBOP Novabiochem? | 128625-52-5 | 100g | $367 | 2024-03-01 | Buy |
Sigma-Aldrich | 12805 | (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate purum, ≥97.0% (TLC) | 128625-52-5 | 1g | $81.9 | 2024-03-01 | Buy |
Sigma-Aldrich | 12805 | (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate purum, ≥97.0% (TLC) | 128625-52-5 | 5G | $96 | 2024-03-01 | Buy |
Sigma-Aldrich | 12805 | (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate purum, ≥97.0% (TLC) | 128625-52-5 | 25g | $298 | 2024-03-01 | Buy |
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl) phosphonium hexafluorophosphate is a peptide coupling reagent utilized in solid phase peptide synthesis. It is also used as a substitute for the (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.
Uses
One of the most convenient coupling reagents for peptide synthesis without carcinogenic by-products. It replaces BOP reagent. This is especially suitable for solid-phase peptide synthesis, avoids racemization.
Uses
Reagent for:
Synthesis of single labeled oligonucleotides that fluoresce upon matched hybridization
Generation of endocrine disruptor chemical binders
Cycloaddition to template-assembled multivalent peptide conjugates
General Description
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification. It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Jiangsu Vcan Advanced Material Co., Ltd. | +86-17306299870 +86-18652789875 | vcanam@vcanam.com | China | 32 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12837 | 58 |
Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046 | sales01@watsonbiotech.cn | China | 5822 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18648 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21639 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32820 | 60 |
AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
View Lastest Price from Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-02 | Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
128625-52-5
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-02 | PyBOP Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
128625-52-5
|
US $0.00-0.00 / kg | 1kg | 99% | 20MT | Watson Biotechnology Co.,Ltd | ||
2024-10-17 | PyBOP
128625-52-5
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd |
- Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
128625-52-5
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- PyBOP Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
128625-52-5
- US $0.00-0.00 / kg
- 99%
- Watson Biotechnology Co.,Ltd
- PyBOP
128625-52-5
- US $0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
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