ChemicalBook >> CAS DataBase List >>Crotonyl fentanyl

Crotonyl fentanyl

CAS No.
760930-59-4
Chemical Name:
Crotonyl fentanyl
Synonyms
Crotonyl fentanyl;Crotonyl fentanyl (CRM);2-Butenamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-, (2E)-
CBNumber:
CB64666369
Molecular Formula:
C23H28N2O
Molecular Weight:
348.48
MDL Number:
MOL File:
760930-59-4.mol
Last updated:2023-06-08 09:02:52

Crotonyl fentanyl Properties

solubility DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form A neat solid
FDA UNII R0XLG8CO63

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H312-H302-H332
Precautionary statements  P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501
DEA Controlled Substances CSCN: 9844
CSA SCH: Schedule I
NARC: Yes
NFPA 704
0
3 0

Crotonyl fentanyl Chemical Properties,Uses,Production

Description

Crotonyl fentanyl is an analytical reference material categorized as an opioid.1,2,3 Crotonyl fentanyl induces generalized responses in mice trained to discriminate oxycodone from saline.4 Crotonyl fentanyl is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

Uses

Crotonyl Fentanyl is an analog of Fentanyl (F274990), which is a controlled substanced used as analgesic.

References

1. Eshleman, A.J., Nagarajan, S., Wolfrum, K.M., et al. Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors Biochem. Pharmacol. 182,114293(2020).
2. Vasudevan, L., Vandeputte, M.M., Deventer, M., et al. Assessment of structure-activity relationships and biased agonism at the mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform Biochem. Pharmacol. 177,113910(2020).
3. Varshneya, N.B., Walentiny, D.M., Moisa, L.T., et al. Opioid-like antinociceptive and locomotor effects of emerging fentanyl-related substances Neuropharmacology 151,171-179(2019).
4. Walentiny, D.M., Moisa, L.T., and Beardsley, P.M. Oxycodone-like discriminative stimulus effects of fentanyl-related emerging drugs of abuse in mice Neuropharmacology 150,210-216(2019).

Crotonyl fentanyl Preparation Products And Raw materials

Raw materials

Preparation Products

Crotonyl fentanyl Crotonyl fentanyl (CRM) 2-Butenamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-, (2E)- 760930-59-4