SB 200646 HYDROCHLORIDE
- CAS No.
- 143797-62-0
- Chemical Name:
- SB 200646 HYDROCHLORIDE
- Synonyms
- SB-200646A;SB 200646A,SB200646A;SB 200646 hydrochloride, 5-HT2C/2B receptor antagonist
- CBNumber:
- CB6497473
- Molecular Formula:
- C15H14N4O.ClH
- Molecular Weight:
- 302.763
- MDL Number:
- MFCD00913519
- MOL File:
- 143797-62-0.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
SB 200646 HYDROCHLORIDE price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | S155033 | SB200646Hydrochloride | 143797-62-0 | 50mg | $865 | 2021-12-16 | Buy |
| ApexBio Technology | B5104 | SB200646hydrochloride | 143797-62-0 | 50mg | $959 | 2021-12-16 | Buy |
| ChemScene | CS-0024588 | SB-200646A 99.47% | 143797-62-0 | 100mg | $760 | 2021-12-16 | Buy |
| ChemScene | CS-0024588 | SB-200646A 99.47% | 143797-62-0 | 5mg | $110 | 2021-12-16 | Buy |
| ChemScene | CS-0024588 | SB-200646A 99.47% | 143797-62-0 | 50mg | $480 | 2021-12-16 | Buy |
SB 200646 HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
SB 200646 Hydrochloride is a 5-HT2C antagonist.
in vivo
SB-200646A (20 mg/kg; intravenous injection; daily; for 21 days; male albino Sprague-Dawley rats) treatment significantly decreases the number of spontaneously active ventral tegmental area (VTA) dopaminergic neurons[1].
The i.v. administration of 4-16 mg/kg of SB-200646A significantly increases the firing rate and % events as bursts in spontaneously active VTA dopaminergic neurons and significantly increases the % events as burst in substantia nigra pars compacta (SNC) dopaminergic neurons[1].
| Animal Model: | Male albino Sprague-Dawley rats (200-225 g at the beginning of treatment and 300-350 g at the time of the experiment)[1] |
| Dosage: | 20 mg/kg |
| Administration: | Intravenous injection; daily; for 21 days |
| Result: | Significantly decreased the number of spontaneously active ventral tegmental area (VTA) dopaminergic neurons. |
IC 50
5-HT2B Receptor: 7.5 (pKi); 5-HT2C Receptor: 6.9 (pKi); 5-HT2A Receptor: 5.2 (pKi)
SB 200646 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
SB 200646 HYDROCHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32202 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38636 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 6345 | 55 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4997 | 58 |
View Lastest Price from SB 200646 HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | SB-200646A
143797-62-0
|
US $35.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- SB-200646A
143797-62-0
- US $35.00 / mg
- TargetMol Chemicals Inc.
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