ChemicalBook >> CAS DataBase List >>SB-756050
SB-756050
- CAS No.
- 447410-57-3
- Chemical Name:
- SB-756050
- Synonyms
- SB-756050;SB-756050, >98%;SB756050;SB 756050;SB-756050;1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane;1H-1,4-Diazepine, 1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]hexahydro-;G protein-coupled Bile Acid Receptor 1,inhibit,TGR5,Inhibitor,SB756050,GPBAR1,G-protein coupled receptor 19,GPCR19
- CBNumber:
- CB93162605
- Molecular Formula:
- C21H28N2O8S2
- Molecular Weight:
- 500.59
- MDL Number:
- MFCD02585318
- MOL File:
- 447410-57-3.mol
Last updated:2023-09-04 16:42:00
| Boiling point | 653.1±65.0 °C(Predicted) |
|---|---|
| Density | 1.328±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.25 mg/ml; DMSO: 10 mg/ml |
| form | A crystalline solid |
| pka | -6.97±0.20(Predicted) |
| FDA UNII | F3EST236LD |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
SB-756050 price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 27998 | SB-756050 | 447410-57-3 | 50mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 27998 | SB-756050 | 447410-57-3 | 100mg | $208 | 2024-03-01 | Buy |
| Cayman Chemical | 27998 | SB-756050 | 447410-57-3 | 10mg | $33 | 2024-03-01 | Buy |
| ChemScene | CS-6960 | SB756050 99.32% | 447410-57-3 | 10mg | $75 | 2021-12-16 | Buy |
| ChemScene | CS-6960 | SB756050 99.32% | 447410-57-3 | 25mg | $135 | 2021-12-16 | Buy |
SB-756050 Chemical Properties,Uses,Production
Description
SB-756050 is an agonist of the bile acid G protein-coupled receptor TGR5 (EC50 = 1.3 μM for the human receptor). It is selective for TGR5 over the farnesoid X receptor (FXR) and a panel of other receptors, channels, and transporters. SB-756050 (10-100 mg/kg) decreases fasting glucose levels and increases glucose disposal rate and insulin secretion in diabetic Goto Kakizaki rats.
SB-756050 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 50)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4667 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Shanghai JiYi Biotechnology Co. Ltd. | 13621943973 | sales@shjiyipharmatech.com | China | 1166 | 55 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3552 | 55 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8019 | 62 |
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SB-756050
1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane
SB756050;SB 756050;SB-756050
SB-756050, >98%
1H-1,4-Diazepine, 1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]hexahydro-
G protein-coupled Bile Acid Receptor 1,inhibit,TGR5,Inhibitor,SB756050,GPBAR1,G-protein coupled receptor 19,GPCR19
447410-57-3