3,6-DIHYDROXYXANTHONE
- CAS No.
- 529-61-3
- Chemical Name:
- 3,6-DIHYDROXYXANTHONE
- Synonyms
- Eyxanthone;IFLAB-BB F0349-4255;1,7-DIHYDROXYXANTHONE;3,6-DIHYDROXYXANTHONE;1,7-Dihydroxy-9H-xanthen-9-one;9H-Xanthen-9-one, 1,7-dihydroxy-
- CBNumber:
- CB6698357
- Molecular Formula:
- C13H8O4
- Molecular Weight:
- 228.2
- MDL Number:
- MFCD00914848
- MOL File:
- 529-61-3.mol
- MSDS File:
- SDS
3,6-DIHYDROXYXANTHONE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM0304331 | 1,7-DIHYDROXY-9H-XANTHEN-9-ONE 95.00% | 529-61-3 | 5MG | $500.78 | 2021-12-16 | Buy |
| Crysdot | CD32001075 | Euxanthone 95+% | 529-61-3 | 5mg | $720 | 2021-12-16 | Buy |
| Arctom | CFN98879 | Euxanthone ≥98% | 529-61-3 | 5mg | $283 | 2021-12-16 | Buy |
3,6-DIHYDROXYXANTHONE Chemical Properties,Uses,Production
Uses
Euxanthone, a xanthone derivative, attenuates Aβ1-42-induced oxidative stress and apoptosis by triggering autophagy. Euxanthone exhibits anti-neoplastic and neuroprotective activities[1][2][3].
Definition
ChEBI: A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1 and 7 and an oxo group at position 9. It has been isolated from Cratoxylum cochinchinense.
Synthesis Reference(s)
Synthetic Communications, 19, p. 1641, 1989 DOI: 10.1080/00397918908051061
in vivo
Euxanthone (40-80 mg/kg) could significantly decrease the number of metastatic nodules in lung tissue in a pulmonary metastasis model[1].
Euxanthone (30-60 mg/kg; p.o.;once a day; for 7 days) treatment normalized Bnip3, Beclin1, Pink1, Parkin, p53, Bax, caspase-3, and LC3 II/I in bearing bilateral common carotid artery occlusion (BCCAO). Euxanthone modulates mitophagy and apoptosis induces by mitochondrial stress mediated by mitochondrial fragmentation[2].
| Animal Model: | Forty male ICR mice (20 g) induced cerebral ischemia and reperfusion[2] |
| Dosage: | 30 mg/kg, 60 mg/kg |
| Administration: | p.o.;once a day; for 7 days |
| Result: | Markedly attenuated BCCAO triggered mitochondrial stress and related breakdown. |
References
[1] Xiaodong Chen, et al. Euxanthone Impairs the Metastatic Potential of Osteosarcoma by Reducing COX-2 Expression. Anat Rec (Hoboken). 2019 Aug;302(8):1399-1408. DOI:10.1002/ar.23992
[2] Wei Sun, et al. Euxanthone improves cognitive impairment by attenuating mitochondrial fragmentation and suppressing oxidative stress. Cent Eur J Immunol. 2021;46(4):446-455. DOI:10.5114/ceji.2021.111444
[3] aicheng Yuan, et al. Euxanthone Attenuates Aβ1-42-Induced Oxidative Stress and Apoptosis by Triggering Autophagy. J Mol Neurosci. 2018 Dec;66(4):512-523. DOI:10.1007/s12031-018-1175-2
3,6-DIHYDROXYXANTHONE Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
3,6-DIHYDROXYXANTHONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1087@dideu.com | China | 3270 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5653 | 65 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7787 | 56 |
View Lastest Price from 3,6-DIHYDROXYXANTHONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-01-03 | 1,7-Dihydroxy-9H-xanthen-9-one
529-61-3
|
US $0.00-0.00 / KG | 5mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2024-10-28 | Euxanthone
529-61-3
|
US $195.00 / mg | 98% | 10g | TargetMol Chemicals Inc. |
-
- 1,7-Dihydroxy-9H-xanthen-9-one
529-61-3
- US $0.00-0.00 / KG
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-
- Euxanthone
529-61-3
- US $195.00 / mg
- 98%
- TargetMol Chemicals Inc.