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rac 4-Hydroxy Ephedrine Hydrochloride

rac 4-Hydroxy Ephedrine Hydrochloride structure

CAS No.: 365-26-4

Chemical Name:: rac 4-Hydroxy Ephedrine Hydrochloride

Synonyms: Suprifen;Supriphen;Oxyephedrin;Oxyephedrine;MethylsyMpatol;4-Hydroxyephedrine;METHYLSYNEPHRINE(P);1-Hydroxypholedrine;(±)-Hydroxyephedrine;rac 4-Hydroxy Ephedrine

CBNumber:: CB6889490

Molecular Formula:: C10H15NO2

Molecular Weight:: 181.23

MDL Number:

MOL File:: 365-26-4.mol

MSDS File:: SDS

Last updated:2024-08-02 15:22:07

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rac 4-Hydroxy Ephedrine Hydrochloride Properties

Melting point	152-154°
Boiling point	314.35°C (rough estimate)
Density	1.0918 (rough estimate)
refractive index	1.5464 (estimate)
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	9.97±0.26(Predicted)
InChI	InChI=1S/C10H15NO2/c1-7(11-2)10(13)8-3-5-9(12)6-4-8/h3-7,10-13H,1-2H3
InChIKey	OXFGTKPPFSCSMA-UHFFFAOYSA-N
SMILES	C1(=CC=C(O)C=C1)C(O)C(C)NC
FDA UNII	F49638UBDR

rac 4-Hydroxy Ephedrine Hydrochloride price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	300632	Methylsynephrine Hydrochloride	365-26-4	20mg	$277	2021-12-16	Buy
American Custom Chemicals Corporation	API0010553	4-[1-HYDROXY-2-(METHYLAMINO)PROPYL]PHENOL 95.00%	365-26-4	10MG	$750.75	2021-12-16	Buy
American Custom Chemicals Corporation	API0010553	4-[1-HYDROXY-2-(METHYLAMINO)PROPYL]PHENOL 95.00%	365-26-4	100MG	$1963.5	2021-12-16	Buy
Arctom	CFN92450	MethylsynephrineHydrochloride	365-26-4	5mg	$288	2021-12-16	Buy

Product number	Packaging	Price	Buy
300632	20mg	$277	Buy
API0010553	10MG	$750.75	Buy
API0010553	100MG	$1963.5	Buy
CFN92450	5mg	$288	Buy

rac 4-Hydroxy Ephedrine Hydrochloride Chemical Properties,Uses,Production

Originator

Carnigen, Aventis Pharma Deutschland

Manufacturing Process

The p-benzyloxypropiophenone used for the transformation is prepared by adding to a solution of 6.9 g of sodium in 230 ml of absolute alcohol 45.0 g of p-hydroxypropiophenone and 54.0 g of benzyl bromide, and boiling for 1 h in a reflux apparatus. The excess of alcohol is then distilled and the residue is extracted with ether and water. After drying it the ethereal solution is evaporated and the residue is recrystallized from alcohol of 95% strength. The yield amounts to 60.0 g. The p-benzyloxypropiophenone melts at 100°-101°C.
55.0 g of p-benzyloxypropiophenone are dissolved in 250 ml of methylene chloride and brominated with 38.0 g of bromine. As soon as all of the bromine has been introduced drop by drop, the methylene chloride solution is washed with caustic soda solution and water. The solvent is eliminated in a vacuum and the residue is dissolved in petroleum ether. The crystalline mass which soon separates is filtered by suction and washed with petroleum ether. When recrystallized from hexahydrobenzene the p-benzyloxybromopropiophenone melts at 80°C.
40.0 g of p-benzyloxybromopropiophenone are then transformed in an alcoholic solution with 30.0 g of methylbenzylamine. After the whole has been allowed to stand for 1 day, the excess of alcohol is distilled in a vacuum and the residue is dissolved with ether. By washing with water, the benzylmethylamine hydrobrornide then formed is eliminated and the ether is removed by evaporation. The ether residue soon begins to crystallize and the p-benzyloxymethylbenzylaminopropriophenone is obtained with a good yield; when recrystallized from petroleum ether of low boiling point it melts at 58°60°C.
15.0 g of p-benzyloxymethylbenzylaminopropriophenone are dissolved in alcohol and the solution is hydrogenated with palladium and hydrogen. As soon as the required quantity of hydrogen has been absorbed the palladium is filtered by suction and the alcohol is evaporated in a vacuum The residue is recrystallized and the p-hydroxyphenylmethylaminopropanol is obtained.

Therapeutic Function

Sympathomimetic, Analeptic

rac 4-Hydroxy Ephedrine Hydrochloride Preparation Products And Raw materials

Raw materials

4'-Hydroxypropiophenone Sodium hydroxide Hydrogen Ethyl acetate Benzyl bromide

Palladium Sodium DL-alpha-Methylbenzylamine

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Preparation Products

rac 4-Hydroxy Ephedrine Hydrochloride Suppliers

Global( 76)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12841	58
Hong Kong Excellence Biotechnology Co., Ltd.		ada@sh-teruiop.com	China	875	58
Sigma Audley	+86-15937194204 +86-18126314766	nova@sh-teruiop.com	China	467	58
Hebei Mojin Biotechnology Co.,Ltd	+86-15028179902	angelia@hbmojin.com	China	1177	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1001	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2930	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8810	58
Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +8613651600618	sales@worldyachem.com	China	1243	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Hong Kong Excellence Biotechnology Co., Ltd.	58
Sigma Audley	58
Hebei Mojin Biotechnology Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanxi Naipu Import and Export Co.,Ltd	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Hubei Jusheng Technology Co.,Ltd.	58
Hebei Weibang Biotechnology Co., Ltd	58
Shanghai Worldyang Chemical Co.,Ltd.	58

View Lastest Price from rac 4-Hydroxy Ephedrine Hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-09-25	(R,S)-4-hydroxy-alpha-[1-(methylamino)ethyl]benzyl alcohol 365-26-4	US $0.00 / kg	1kg	99%	1ton	Wuhan Senwayer Century Chemical Co.,Ltd
2024-09-19	Oxyephedrin 365-26-4	US $100.00 / kg	1kg	99.9%	20tons	Hong Kong Excellence Biotechnology Co., Ltd.
2024-08-14	(R,S)-4-hydroxy-alpha-[1-(methylamino)ethyl]benzyl alcohol 365-26-4	US $0.00 / kg	1kg	99%	50000KG/month	Hebei Mojin Biotechnology Co.,Ltd

(R*,S*)-4-hydroxy-alpha-[1-(methylamino)ethyl]benzyl alcohol
365-26-4
US $0.00 / kg
99%
Wuhan Senwayer Century Chemical Co.,Ltd

Oxyephedrin
365-26-4
US $100.00 / kg
99.9%
Hong Kong Excellence Biotechnology Co., Ltd.

(R*,S*)-4-hydroxy-alpha-[1-(methylamino)ethyl]benzyl alcohol
365-26-4
US $0.00 / kg
99%
Hebei Mojin Biotechnology Co.,Ltd

365-26-4(rac 4-Hydroxy Ephedrine Hydrochloride)Related Search:

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A Kissin Flynn hydrochloride (R*,S*)-4-hydroxy-alpha-[1-(methylamino)ethyl]benzyl alcohol Oxyephedrine rac-4-[(1R*,2S*)-1-Hydroxy-2-(methylamino)propyl]phenol 1-(p-Hydroxyphenyl)-2-(methylamino)-1-propanol 1-Hydroxypholedrine 4-(1-Hydroxy-2-methylaminopropyl)phenol 4-Hydroxy-α-[1-(methylamino)ethyl]benzenemethanol Oxyephedrin METHYLSYNEPHRINE(P) Methylsynephrine Hydrochloride (±)-Hydroxyephedrine (αS)-rel-4-Hydroxy-α-[(1R)-1-(MethylaMino)ethyl]benzeneMethanol 1-(4-Hydroxyphenyl)-1-hydroxy-2-MethylaMinopropane 4-((1S,2R)-rel-1-Hydroxy-2-(MethylaMino)propyl)phenol BenzeneMethanol,4-hydroxy-a-[(1R)-1-(MethylaMino)ethyl]-, (aS)-rel- Methyloctanedioic Flynn hydrochloride 4-Hydroxyephedrine MethylsyMpatol p-hydroxy-α-[1-(MethylaMino)ethyl]benzyl Alcohol rac 4-Hydroxy Ephedrine Suprifen Supriphen (R*,S*)-4-hydroxy-α-[1-(methylamino)ethyl]benzyl alcohol Benzenemethanol, 4-hydroxy-α-[(1R)-1-(methylamino)ethyl]-, (αS)-rel- (R*,S*)-4-hydroxy-alpha-[1-(methylamino)ethyl]benzyl alcohol USP/EP/BP Steroids Raw Powder Methyl Synephrine Hydrochloride Powder CAS 365-26-4 OxilofrineQ: What is Oxilofrine Q: What is the CAS Number of Oxilofrine TAINFUCHEM: (R*,S*)-4-hydroxy-alpha-[1-(methylamino)ethyl]benzyl alcohol (R*,S*)-4-hydroxy-α-[1-(methylamino)ethyl]benzyl alcohol rac 4-Hydroxy Ephedrine Hydrochloride Benzenemethanol, 4-hydroxy-α-[(1R)-1-(methylamino)ethyl]-, (αS)-rel- 365-26-4 7427-54-9