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2-amino-5-methylbenzenesulfonamide

2-amino-5-methylbenzenesulfonamide Structure
2-amino-5-methylbenzenesulfonamide structure
CAS No.
609-55-2
Chemical Name:
2-amino-5-methylbenzenesulfonamide
Synonyms
NSC57677;Pazopanib Impurity 60;2-amino-5-methylbenzenesulfomide;2-amino-5-methylbenzenesulfonamide;2-amino-4-methylbenzenesulfonamide;2-azanyl-5-methyl-benzenesulfonamide;Benzenesulfonamide, 2-amino-5-methyl-;Benzenesulfonamide, 2-amino-5-methyl- (9CI)
CBNumber:
CB71040804
Molecular Formula:
C7H10N2O2S
Molecular Weight:
186.23
MDL Number:
MFCD00800465
MOL File:
609-55-2.mol
Last updated:2023-10-18 09:04:46
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2-amino-5-methylbenzenesulfonamide Properties

storage temp. 2-8°C
InChI InChI=1S/C7H10N2O2S/c1-5-2-3-6(8)7(4-5)12(9,10)11/h2-4H,8H2,1H3,(H2,9,10,11)
InChIKey GKTVIFGJASUBGA-UHFFFAOYSA-N
SMILES C1(S(N)(=O)=O)=CC(C)=CC=C1N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H335-H319-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501

2-amino-5-methylbenzenesulfonamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 9112AB 2-Amino-5-methylbenzenesulfonamide 609-55-2 500mg $786 2021-12-16 Buy
Alichem 609552 2-Amino-5-methylbenzenesulfonamide 609-55-2 500mg $798.7 2021-12-16 Buy
Crysdot CD12055999 2-Amino-5-methylbenzenesulfonamide 95+% 609-55-2 5g $853 2021-12-16 Buy
Alichem 609552 2-Amino-5-methylbenzenesulfonamide 609-55-2 1g $1534.7 2021-12-16 Buy
Alichem 609552 2-Amino-5-methylbenzenesulfonamide 609-55-2 250mg $489.6 2021-12-16 Buy
Product number Packaging Price Buy
9112AB 500mg $786 Buy
609552 500mg $798.7 Buy
CD12055999 5g $853 Buy
609552 1g $1534.7 Buy
609552 250mg $489.6 Buy

2-amino-5-methylbenzenesulfonamide Chemical Properties,Uses,Production

Uses

2-amino-5-methylbenzenesulfonamide is an important organic reagent that can be used as a building block for the synthesis of many organic compounds. It could reacted with triethyl orthoformate to give 7-Methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide by ring closure. It was an intermediate of potent AMPA receptor potentiators[1].

Synthesis

A solution of 7-methyl-3-oxo-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (10, 10 g, 47,12 mmol) in sulfuric acid 50% (150 mL) was refluxed until complete dissolution of the suspension. At the end of the reaction, the solution was adjusted to pH 7 with an aqueous solution of concentrated NaOH. The solvent was removed by distillation under reduced pressure. The residue was triturated with methanol and the salts were eliminated by filtration. The filtrate was concentrated to dryness under reduced pressure and the residue was triturated in water (a minimum). The resulting precipitate was collected by filtration, washed with water, and dried to afford 2-amino-5-methylbenzenesulfonamide[1].

References

[1] Dintilhac G, et al. New substituted aryl esters and aryl amides of 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors. RSC Medicinal Chemistry, 2011; 2: 509-523.

2-amino-5-methylbenzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

2-amino-5-methylbenzenesulfonamide Suppliers

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com China 52849 58
PT CHEM GROUP LIMITED 		+86-85511178; +86-85511178; peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49978 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Chemwill Asia Co.,Ltd. 86-21-51086038 chemwill_asia@126.com CHINA 23912 58
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 sales@capotchem.com China 18207 66
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
PT CHEM GROUP LIMITED 		58
GIHI CHEMICALS CO.,LIMITED 		58
Amadis Chemical Company Limited 		58
Chemwill Asia Co.,Ltd. 58
Capot Chemical Co., Ltd 66

View Lastest Price from 2-amino-5-methylbenzenesulfonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-amino-5-methylbenzenesulfonamide pictures 2019-07-06 2-amino-5-methylbenzenesulfonamide
609-55-2
 US $20.00 / KG 1KG 98% 20kg Career Henan Chemical Co

609-55-2(2-amino-5-methylbenzenesulfonamide)Related Search:

5-Amino-2-methylbenzenesulfonamide 3-Methyl-6-nitroindazole 2-Ethyl-5-nitrobenzenamine ,98% N4-(2,3-Dimethyl-2H-indazol-6-yl)-N4-methyl-2,4-pyrimidinediamine Pazopanib Impurity 48
3-methyl-1H-indazol-6-amine 5-Amino-2,3-dimethyl-2H-indazole Pazopanib Impurity 32 2,4-Dichloropyrimidine Benzenamine, 2-ethyl-4-nitro-
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2-amino-5-methylbenzenesulfonamide Benzenesulfonamide, 2-amino-5-methyl- (9CI) NSC57677 Benzenesulfonamide, 2-amino-5-methyl- 2-azanyl-5-methyl-benzenesulfonamide 2-amino-4-methylbenzenesulfonamide 2-amino-5-methylbenzenesulfomide Pazopanib Impurity 60 609-55-2 SULFONAMIDE