Apigenin-D5
- CAS No.
- 263711-74-6
- Chemical Name:
- Apigenin-D5
- Synonyms
- Apigenin-D5;Apigenin-d5 (Major);Pelargidenon 1449-d5;[3,6,8,35d5]-Apigenin;4',5,7-Trihydroxyflavone-d5;5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5;4H-1-Benzopyran-4-one-3,6,8-d3, 5,7-dihydroxy-2-(4-hydroxyphenyl-3,5-d2)-;3,6,8-trideuterio-2-(3,5-dideuterio-4-hydroxyphenyl)-5,7-dihydroxychromen-4-one
- CBNumber:
- CB71121213
- Molecular Formula:
- C15H5D5O5
- Molecular Weight:
- 0
- MDL Number:
- MFCD09839941
- MOL File:
- 263711-74-6.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
Apigenin-D5 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22106 | Apigenin-d5 ≥99% deuterated forms (d1-d5); ≤1% d0 | 263711-74-6 | 500μg | $145 | 2024-03-01 | Buy |
| Cayman Chemical | 22106 | Apigenin-d5 ≥99% deuterated forms (d1-d5); ≤1% d0 | 263711-74-6 | 1mg | $276 | 2024-03-01 | Buy |
| Usbiological | 002799 | Apigenin-d5 | 263711-74-6 | 1mg | $425 | 2021-12-16 | Buy |
| TRC | A726502 | Apigenin-d5(Major) | 263711-74-6 | 10mg | $1155 | 2021-12-16 | Buy |
| TRC | A726502 | Apigenin-d5(Major) | 263711-74-6 | 1mg | $145 | 2021-12-16 | Buy |
Apigenin-D5 Chemical Properties,Uses,Production
Description
Apigenin-d5 is an internal standard for the quantificaiton of apigenin by GC- or LC-MS. Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase 2 (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC50 value of 30 μM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 μM apigenin decreases the degradation of IκBα and down-regulates NF-κB levels in WEHI-231 cells. Apigenin, at 5 μM, is a potent inhibitor of the synthesis of the inflammatory mediators nitric oxide and prostaglandin E2, reducing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by 56% and 64%, respectively, in the macrophage cell line J774A.1.
Chemical Properties
Pale Yellow Crystalline Solid
Uses
The labelled aglucon of apiin and of apigenin-7-glucoside
Apigenin-D5 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30238 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4496 | 50 | |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57423 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7979 | 58 |