N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE
- CAS No.
- 259143-19-6
- Chemical Name:
- N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE
- Synonyms
- NALT;N-(α-Linolenoyl) Tyrosine;N-(α-Linolenoyl) Tyrosine;DEQLZTQITSWABQ-GMOGWPNXSA-N;N-(ALPHA-LINOLEOYL) TYROSINE;N-(.alpha.-Linolenoyl) Tyrosine;N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE;N (α Linolenoyl) Tyrosine,N(αLinolenoyl) Tyrosine;L-Tyrosine, N-[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]-
- CBNumber:
- CB7124693
- Molecular Formula:
- C27H39NO4
- Molecular Weight:
- 441.6
- MDL Number:
- MFCD08062216
- MOL File:
- 259143-19-6.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
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N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10032 | N-(α-Linolenoyl) Tyrosine ≥98% | 259143-19-6 | 5mg | $71 | 2024-03-01 | Buy |
| Cayman Chemical | 10032 | N-(α-Linolenoyl) Tyrosine ≥98% | 259143-19-6 | 10mg | $133 | 2024-03-01 | Buy |
| Cayman Chemical | 10032 | N-(α-Linolenoyl) Tyrosine ≥98% | 259143-19-6 | 50mg | $554 | 2024-03-01 | Buy |
| Cayman Chemical | 10032 | N-(α-Linolenoyl) Tyrosine ≥98% | 259143-19-6 | 100mg | $968 | 2024-03-01 | Buy |
| AK Scientific | 1890AH | N-(L-Tyrosine)-9Z,12Z,15Z-octadecatrienamide | 259143-19-6 | 50mg | $715 | 2021-12-16 | Buy |
N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Chemical Properties,Uses,Production
Description
Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.1 N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.2 In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.2
Definition
ChEBI: N-(alpha-Linolenoyl) Tyrosine is a tyrosine derivative.
References
1. Martin, J.B. Molecular basis of the neurodegenerative disorders N. Engl. J. Med. 340(25),1970-1980(1999).
2. Yehuda, S. Possible anti-
N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Jiangsu Hongmin Pharmaceutical Co., Ltd. | 18221292452 | fannieliu@glschina.com | China | 6799 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 15102117276 18019707223 | tech@zzbioco.com | China | 12066 | 58 |