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trans-4-Aminocyclohexanol

trans-4-Aminocyclohexanol Structure
trans-4-Aminocyclohexanol structure
CAS No.
27489-62-9
Chemical Name:
trans-4-Aminocyclohexanol
Synonyms
(1r,4r)-4-aminocyclohexanol;(1s,4s)-4-Aminocyclohexanol;trans-4-aminocyclohexan-1-ol;AURORA KA-7506;trans-4-AminocycL;TIMTEC-BB SBB005825;trans-4-Aminocyclohe;Ambroxol Impurity 36;4-(E)-aMino cyclohexano;Ammonia bromine AMB - F
CBNumber:
CB7139383
Molecular Formula:
C6H13NO
Molecular Weight:
115.17
MDL Number:
MFCD00067698
MOL File:
27489-62-9.mol
Last updated:2024-11-21 17:11:28
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trans-4-Aminocyclohexanol Properties

Melting point 108-113°C
Boiling point 127 °C / 14mmHg
Density 0.9837 (rough estimate)
refractive index 1.4713 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystals
pka 15.12±0.40(Predicted)
color White to almost white
Water Solubility Soluble in water.
Sensitive Hygroscopic
LogP -0.4
CAS DataBase Reference 27489-62-9(CAS DataBase Reference)
FDA UNII D6E7B62984

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314-H318
Precautionary statements  P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501-P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P501a
Hazard Codes  Xi,C,Xn
Risk Statements  36/37/38-34-41-37/38-22
Safety Statements  26-37/39-45-36/37/39-39
RIDADR  3259
Hazard Note  Irritant
HazardClass  8
PackingGroup  Ⅲ
HS Code  29221990
NFPA 704
1
3 0

trans-4-Aminocyclohexanol price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A1160 trans-4-Aminocyclohexanol >98.0%(GC) 27489-62-9 25g $33 2024-03-01 Buy
TCI Chemical A1160 trans-4-Aminocyclohexanol >98.0%(GC) 27489-62-9 500g $363 2024-03-01 Buy
Alfa Aesar B22365 trans-4-Aminocyclohexanol 98+% 27489-62-9 5g $42.65 2024-03-01 Buy
Alfa Aesar B22365 trans-4-Aminocyclohexanol 98+% 27489-62-9 25g $138.65 2024-03-01 Buy
Alfa Aesar B22365 trans-4-Aminocyclohexanol 98+% 27489-62-9 100g $408.65 2024-03-01 Buy
Product number Packaging Price Buy
A1160 25g $33 Buy
A1160 500g $363 Buy
B22365 5g $42.65 Buy
B22365 25g $138.65 Buy
B22365 100g $408.65 Buy

trans-4-Aminocyclohexanol Chemical Properties,Uses,Production

Description

Trans-4-Aminocyclohexanol is also named as Cis-4-Aminocyclohexanol. It was a medical intermediate of ambroxol, which is used in the treatment of respiratory diseases associated with viscid or excessive mucus.1 It is used as a raw material in organic synthesis, such as in the synthesis of N-substituted 7-azabicyclo [2.2.1] hepatanes, which are good substrates for microbial oxidation of unactivated carbons by B.bassiana.2

Reference

  1. Y. Jian, Improved Process of the Synthesis of Trans-4-aminocyclohexanol, Fine Chemicals, 2000, vol. 2
  2. H. F. Olivo, M. S. Hemenway, M. H. Gezginci, Synthesis and Microbial Hydroxylation of Some Azabicycloalkanes, Tetrahedron Letters, 1998, vol. 39, pp. 1309-1312

Chemical Properties

white to light yellow crystal powder

Uses

trans-4-Aminocyclohexanol is used as raw material in organic synthesis and is an important intermediate in the synthesis of drugs such as Ambroxol hydrochloride. It can react with butyric acid-(2-chloro-ethyl ester) to get butyric acid 4-amino-cyclohexyl ester. This reaction needs catalytic agent Aspergillus niger lipase and solvent 2-methyl-butan-2-ol.

Uses

trans-4-aminocyclohexanol be used as organic intermediates.

trans-4-Aminocyclohexanol Preparation Products And Raw materials

Raw materials

1,4-Cyclohexanedione Lithium Aluminum Hydride 4-Nitrophenol P-NITROSOTOLUENE 4-Aminophenol
Hydroquinone

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Preparation Products

4-(Phthalimide)cyclohexanol 2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole TRANS-4-ACETAMIDOCYCLOHEXANOL trans-1,4-Diaminocyclohexane Ambroxol hydrochloride

trans-4-Aminocyclohexanol Suppliers

Global( 547)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8806 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531153977 allison@yan-xi.com China 5857 58
airuikechemical co., ltd. 		+86-18353166132 +86-18353166132 sales02@airuikechemical.com China 983 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3002 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29793 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18750 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714 FandaChem@Gmail.com China 8791 55
Jiangsu Qingquan Chemical Co., Ltd. 		+86-571-86589381,86589382,86589383 sales1@qqpharm.com CHINA 154 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32956 60
Supplier Advantage
Hebei Weibang Biotechnology Co., Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
airuikechemical co., ltd. 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Jiangsu Qingquan Chemical Co., Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60

View Lastest Price from trans-4-Aminocyclohexanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Trans-4-Aminocyclohexanol pictures 2025-01-08 Trans-4-Aminocyclohexanol
27489-62-9
 US $180.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
Trans-4-aminocyclohexanol pictures 2024-12-24 Trans-4-aminocyclohexanol
27489-62-9
 US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
trans-4-Aminocyclohexanol pictures 2024-11-21 trans-4-Aminocyclohexanol
27489-62-9
 US $10.00 / KG 100KG 99% 100 mt Hebei Weibang Biotechnology Co., Ltd

trans-4-Aminocyclohexanol Spectrum

trans-4-Aminocyclohexanol(27489-62-9)MStrans-4-Aminocyclohexanol(27489-62-9)1HNMRtrans-4-Aminocyclohexanol(27489-62-9)13CNMRtrans-4-Aminocyclohexanol(27489-62-9)IR1trans-4-Aminocyclohexanol(27489-62-9)IR2

27489-62-9(trans-4-Aminocyclohexanol)Related Search:

Molasses 1-Methylcyclohexanol Cyclohexanol trans-4-Aminocyclohexanol hydrochloride 2-Aminocyclohexanol
trans,trans-2,4-Undecadienal Cyclamic acid 4-Aminocyclohexanol Cyclohexanol, 4-amino-1-methyl-, trans- (9CI) (E,E)-2,4-Hexadien-1-ol
TRANS-4-AMINO-CYCLOHEXANE CARBOXYLIC ACID HYDROCHLORIDE trans-4-Aminocyclohexanecarbonitrile Methyl trans-4-AMinocyclohexanecarboxylate Hydrochloride Trans-4-Propylcyclohexyl-Benzene Trans-1-(bromomethyl)-4-propylcyclohexane
4-(trans-4-Propylcyclohexyl)phenol trans-4-(4n-Heptylcyclohexyl)phenol trans-4-ethylcyclohexylbenzene

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trans-4-Aminocyclohexanol,97% trans-4-Aminocyclohexanol Trans-4-Amimocyclohexanol Cyclohexanol, 4-amino-, trans- (1α)-4β-Aminocyclohexanol trans-4-Aminocyclohexanol ,99% trans-4-Aminocyclohe Trans-4-aMniocyclohexanol 4-trans-Hydroxycyclohexylamine 4-(E)-aMino cyclohexano Trans-4-aMino cyclohexanol (TACH) trans-4-Aminocyclohexanol The trans-aminocyclohexanol trans-1-amino-4-cyclohexanol TIMTEC-BB SBB005825 TRANS-4-AMINO-1-HYDROXYCYCLOHEXANE AMINOCYCLOHEXANOL(TRANS-4) 4-Trans amino cyclohexanol trans-4-Aminocyclohexanol, 98+% AURORA KA-7506 trans-4-hydroxycyclohexylamine trans-4-Aminocyclohexanol 97% Trans-4-Aminocyclohexanol ( For Ambroxol Hcl ) trans-4-AminocycL Ambroxol Hydrochloride Impurity 4 trans-4-Aminocyclohexanol> Ammonia bromine AMB - F Ambroxol Impurity 36 Trans-4-Amonocyclohexanol Trans-4-amino cyclohexyl phenol (1r,4r)-4-aminocyclohexanol (1s,4s)-4-Aminocyclohexanol trans-4-aminocyclohexan-1-ol Anti-4-amino cyclohexanol rans-4-Aminocyclohexanol (1r,4r)-4-aminocyclohexan-1-ol (1r,4r)-4-aminocyclohexanol/trans-4-Aminocyclohexanol 27489-62-9 50910-58-5 27489-63-9 chiral Amines blocks BuildingBlocks Ambroxol 1