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4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Structure
4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene structure
CAS No.
461432-23-5
Chemical Name:
4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
Synonyms
4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene;Dapagliflozin Bromo impurity;Benzene, 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]-;Dapagliflozin-13;Dapaglifozin DAP Bromo;5-broMo-2-chloro-4’Dapagliflozin Impurity 15;4-(Dibenzofuranyl)boronic;Dapagliflozin Impurity 82;Dapagliflozin Intermediate 1
CBNumber:
CB71456759
Molecular Formula:
C15H14BrClO
Molecular Weight:
325.63
MDL Number:
MFCD11042292
MOL File:
461432-23-5.mol
Last updated:2024-11-13 21:11:14
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4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Properties

Boiling point 393.0±32.0 °C(Predicted)
Density 1.371±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
form Low-Melting Solid
color White to Off-White
Stability Stable under recommended storage conditions., Stable Under Recommended Storage C
InChI InChI=1S/C15H14BrClO/c1-2-18-14-6-3-11(4-7-14)9-12-10-13(16)5-8-15(12)17/h3-8,10H,2,9H2,1H3
InChIKey ZUNCHZBITMUSRD-UHFFFAOYSA-N
SMILES C1(Cl)=CC=C(Br)C=C1CC1=CC=C(OCC)C=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2909309090

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B682175 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene 461432-23-5 1g $460 2021-12-16 Buy
Biosynth Carbosynth FB76075 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene 461432-23-5 50g $500 2021-12-16 Buy
ChemScene CS-B0023 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene 98.57% 461432-23-5 100g $158 2021-12-16 Buy
Biosynth Carbosynth FB76075 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene 461432-23-5 10g $180 2021-12-16 Buy
Matrix Scientific 083813 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether 97% 461432-23-5 5g $242 2021-12-16 Buy
Product number Packaging Price Buy
B682175 1g $460 Buy
FB76075 50g $500 Buy
CS-B0023 100g $158 Buy
FB76075 10g $180 Buy
083813 5g $242 Buy

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Chemical Properties,Uses,Production

Uses

5-Bromo-2-chloro-4'-ethoxydiphenylmethane is a hydrocarbon derivative and can be used as an intermediate for dapagliflozin.

Synthesis

Oxalyl chloride (0.8 mL) was added to a solution of 5-bromo-2-chlorobenzoic acid (2 g) in dichloromethane (20 mL) and dimethylformamide (0.2 mL) under a nitrogen atmosphere. The reaction mixture was stirred for one hour at 25° C to 30° C. After completion of the reaction, the reaction mixture was concentrated under a vacuum at 40° C to 45° C. to obtain an oily residue. The oily residue was dissolved in dichloromethane (20 mL) and cooled to 0° C. To this solution, phenol (1.1 mL) and aluminium chloride (2.3 g) were added at 0° C. to 5° C. The reaction mixture was stirred at 0° C to 5° C for 2 hours. The reaction mixture was allowed to warm to about 20° C, and triethylsilane (3.4 mL) was slowly added to it at the same temperature. The reaction mixture was stirred for about 36 hours from 20° C to 25° C. After completion of the reaction, 4-bromo-1-chloro-2-(4-ethoxybenzyl)benzene was obtained by further purification.

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene synthesis

461432-22-4
461432-23-5
Synthesis of 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene from (5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,3R,4S,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6,6-bis(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol Bexagliflozin 4-(5-broMo-2-chlorobenzyl)phenol

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Suppliers

Global( 556)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Rochi Pharmaceutical Co.,Ltd.
21-38751876 +8615000076078 info@rochipharma.com China 431 58
Suzhou Nordica Biopharma CO.,LTD
+86-18136148818 +86-18567353071 3537297702@qq.com China 299 58
Hebei Mojin Biotechnology Co., Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12840 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5893 58
Shanghai Joiny Pharmaceutical Co.,LTD 		+8613681955282 gyd@joiny-pharma.com China 255 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2472 58
Hangzhou ICH Biofarm Co., Ltd 		+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 998 58
Anhui Lianchuang Biological Medicine Co.,Ltd 		+8613706129682 tiffany@langyupharm.com China 86 58
Hebei Xinsheng New Material Technology Co., LTD. 		+86-16632316109 xinshengkeji@xsmaterial.com China 1085 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858 daisy@anhuiruihan.com China 973 58
Supplier Advantage
Shanghai Rochi Pharmaceutical Co.,Ltd.
58
Suzhou Nordica Biopharma CO.,LTD
58
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Shanghai Joiny Pharmaceutical Co.,LTD 		58
Henan Bao Enluo International TradeCo.，LTD 		58
Hangzhou ICH Biofarm Co., Ltd 		58
Anhui Lianchuang Biological Medicine Co.,Ltd 		58
Hebei Xinsheng New Material Technology Co., LTD. 		58
Anhui Ruihan Technology Co., Ltd 		58

View Lastest Price from 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-bromo-2-chloro-4'-ethoxydiphenylmethane pictures 2024-11-21 5-bromo-2-chloro-4'-ethoxydiphenylmethane
461432-23-5
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
5-bromo-2-chloro-4’-ethoxydiphenylmethane pictures 2024-11-21 5-bromo-2-chloro-4’-ethoxydiphenylmethane
461432-23-5
 US $0.00-0.00 / kg 1kg 98%-101% 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
5-bromo-2-chloro-4’-ethoxydiphenylmethane pictures 2024-11-21 5-bromo-2-chloro-4’-ethoxydiphenylmethane
461432-23-5
 US $999.00-666.00 / kg 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

461432-23-5(4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene)Related Search:

2-(5-BroMo-2-Methylbenzyl)-5-(4-fluorophenyl)thiophene (R)-3-(4-(5-broMo-2-chlorobenzyl)phenoxy)tetrahydrofuran 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone 4-(5-broMo-2-chlorobenzyl)phenol 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene
Empagliflozin Canagliflozin heMihydrate PF-04971729 Ipragliflozin Canagliflozin
2,3,4,6-TETRA-O-PIVALOYL-ALPHA-D-GLUCOPYRANOSYL BROMIDE Donepezil 1-Chloro-2-(4-ethoxybenzyl)-4-iodobenzene 5-Bromo-2-chlorobenzoic acid (5-broMo-2-chlorophenyl)(2-ethoxyphenyl)Methanone
(5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone 4-BROMO-1-CHLORO-2-ETHYLBENZENE 5-bromo-2-chloro-4’-ethoxydiphenylmethane

1of4

5-bromo-2-chloro-4’-ethoxydiphenylmethane 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether Dapagliflozin Intermediate 1 4-broMo-1-chloro-2-[(4-ethoxyphenyl)Methyl]- 2-(4-Methoxybenzyl)-4-broMo-1-chlorobenzene 1-(5-broMo-2-chlorobenzyl)-4-ethoxybenzene 5-broMo-2-chloro-4&rsquo Dapagliflozin Intermediate II Dapagliflozin Intermediate 2 5-bromo-2-chloro-4'-ethoxydiphenylmethane###461432-23-5 (5-bromo-2-chlorobenzyl)-4-ethoxybenzene 4-(5-Brom-2-chlorbenzyl)phenyl-ethylether Dapagliflozin Impurity 15 Dapagliflozin-13 4-(Dibenzofuranyl)boronic 4-(5-Bromo-2-chlorobenzy)phenylethyl ester Dapagliflozin Impurity 82 4-Bromo-1-chloro-2-(4-ethoxybenzyl) Dapagliflozin Despyranose Bromo Impurity 4-Brom-1-chlor-2-(4-ethoxybenzyl)benzol 5-bromo-2-chloro-4’-ethoxydiphenylmethane ISO 9001：2015 REACH 4-(3-((1-ethoxyethoxy)methyl)-4-bromophenoxy)benzonitrile Supply 5-bromo-2-chloro-4'-ethoxydiphenylmethane Dapaglifozin DAP Bromo 5-bromo-2-chloro-4-ethoxydiphenylmethaneQ: What is 5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What is the CAS Number of 5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What is the storage condition of 5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What are the applications of 5-bromo-2-chloro-4-ethoxydiphenylmethane Benzene, 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]- Dapagliflozin Bromo impurity 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene Dapagliflozin Intermediate/ 5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane 4-(5- bromo -2- chlorobenzyl) phenethyl ether 5-Bromo-2-chIoro-4’-ethoxydiphenyImethane 4-Bromo-1-ChIoro 2-4-EthoxybenzyI-Benzene 4-bromo-l-chloro-2-(4-ethoxybenzyl)benzene 2-(4-ethoxybenzyl)-4-bromo-1-chloro benzene 5-bromo-2-chloro-4’-ethoxydiphenylmethane, Or 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether (5-Bromo-2-chlorobenzyl)phenyl ethyl ether 5-bromo-2-chloro-4'-ethoxydiphenylmethane 6-bromo-2-chloro-4’-ethoxydiphenylmethane 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene 461432-23-5 61432-23-5 100134-06-9 9461432-23-5 C15H14BrClO Halides Phenyls & Phenyl-Het 461432-23-5 ADVANCED INT.