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Pyridine-4-boronic acid

CAS No.
1692-15-5
Chemical Name:
Pyridine-4-boronic acid
Synonyms
PYRIDIN-4-YLBORONIC ACID;4-PYRIDYLBORONIC ACID;4-PYRIDINYLBORONIC ACID;4-PYRIDINEBORONIC ACID;Pyridin-4-ylboronic acid, 97%, May contain varying aMounts of anhydride;AKOS BRN-0273;4-Boronopyridine;BUTTPARK 43\57-08;4-Pyridineboronic;TIMTEC-BB SBB004280
CBNumber:
CB7220144
Molecular Formula:
C5H6BNO2
Molecular Weight:
122.92
MDL Number:
MFCD01074545
MOL File:
1692-15-5.mol
MSDS File:
SDS
Last updated:2024-11-27 17:31:30

Pyridine-4-boronic acid Properties

Melting point >300 °C (lit.)
Boiling point 308.8±34.0 °C(Predicted)
Density 1.22±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Aqueous Acid (Slightly), Water (Slightly)
form Solid
pka 7.59±0.10(Predicted)
color White to Off-White
BRN 471944
InChIKey QLULGIRFKAWHOJ-UHFFFAOYSA-N
CAS DataBase Reference 1692-15-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn,Xi,C,F
Risk Statements  36/37/38-22-34-11
Safety Statements  22-24/25-36/37/39-26-45-16
WGK Germany  3
Hazard Note  Irritant
HazardClass  IRRITANT, KEEP COLD
HS Code  29339900
NFPA 704
1
2 0

Pyridine-4-boronic acid price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 634492 4-Pyridinylboronic acid 90% 1692-15-5 1g $43.1 2024-03-01 Buy
Sigma-Aldrich 634492 4-Pyridinylboronic acid 90% 1692-15-5 5g $112 2024-03-01 Buy
TCI Chemical P1594 4-Pyridylboronic Acid (contains varying amounts of Anhydride) 1692-15-5 1g $20 2024-03-01 Buy
TCI Chemical P1594 4-Pyridylboronic Acid (contains varying amounts of Anhydride) 1692-15-5 5g $64 2024-03-01 Buy
Alfa Aesar L15179 Pyridine-4-boronic acid hydrate, ca 10-15% water 1692-15-5 5g $118 2021-12-16 Buy
Product number Packaging Price Buy
634492 1g $43.1 Buy
634492 5g $112 Buy
P1594 1g $20 Buy
P1594 5g $64 Buy
L15179 5g $118 Buy

Pyridine-4-boronic acid Chemical Properties,Uses,Production

Uses

Pyridine-4-boronic acid can be used as a candidate for Suzuki-Miyaura coupling reaction. Especially, as a N-containing building blocks, pyridine-4-boronic acid was employed to construct some heterocyclic compounds with superior biological activities.

Description

Pyridine-4-boronic acid is a kind of boronic acid derivative. It is useful building blocks in crystal engineering. It can also be used as a catalyst to act as a dehydrative condensation agent to synthesize amides using carboxylic acid and amines as raw materials. Its derivative, polystyrene-bound 4-pyridineboronic acid, is a useful catalyst for amidation reaction and esterification of alpha-hydrocarboxylic acids.

Chemical Properties

light orange granular powder

Uses

Boronic acid derivatives and their binding affinities with diols.

Uses

Reagent used for

  • Palladium-catalyzed Suzuki-Miyaura coupling reactions
  • Ligand-free palladium-catalyzed Suzuki coupling reaction under microwave irradation

Reagent used in Preparation of
  • HIV-1 protease inhibitors
  • Potential cancer threapeutics, such as PDK1 and protein kinase CK2 inhibitors

Uses

suzuki reaction

References

http://www.wako-chem.co.jp/english/labchem/product/Org/pyridineboronic/
José J. CamposGaxiola et al. "Pyridineboronic Acids as Useful Building Blocks in Combination with Perchloroplatinate(II) and -(IV) Salts: 1D, 2D, and 3D Hydrogen-Bonded Networks Containing X-H•••Cl2Pt− (X = C, N+), B(OH)2•••Cl2Pt−, and B(OH)2•••(HO)2B Synthons." Crystal Growth & Design 10.7(2010).
Kara, H., A. G. Orpen, and T. J. Podesta. "Pyridine boronic acids as building blocks in crystal engineering." Acta Crystallographica 61.Suppl (2001): C357.

1120-87-2
121-43-7
7732-18-5
1692-15-5
Synthesis of Pyridine-4-boronic acid from 4-Bromopyridine and Trimethyl borate and Water
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View Lastest Price from Pyridine-4-boronic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pyridine-4-boronic acid pictures 2024-11-28 Pyridine-4-boronic acid
1692-15-5
US $10.00 / kg 1kg 99% 20 ton Hebei Zhuanglai Chemical Trading Co Ltd
Pyridine-4-boronic acid pictures 2023-11-27 Pyridine-4-boronic acid
1692-15-5
US $0.00-0.00 / kg 1kg 99.9% 30000 Kg Hebei Xinsheng New Material Technology Co., LTD.
3-Pyridylboronic acid pictures 2023-10-28 3-Pyridylboronic acid
1692-15-5
US $35.00-25.00 / kg 1kg 99% 20 Ton Hebei Xinsheng New Material Technology Co., LTD.
4-Boronopyridine Pyridin-4-bronic Acid PYRIDYL-4-BORONIC ACID PYRIDINE-4-BORONIC ACID PYRIDINE-4-BORONIC ACID HYDRATE PYRIDIN-4-YL-4-BORONIC ACID RARECHEM AH PB 0240 TIMTEC-BB SBB004280 AKOS BRN-0273 4-PYRIDINEBORNIC ACID BUTTPARK 43\57-08 CHEMBRDG-BB 3200984 4-Pyridineboronic Boronic acid, B-4-pyridinyl- 4-Pyridinylboronic acid 90% 4 - pyridine boric acid Pyridine-4-boronic acid Pyridin-4-ylboronic acid PYRIDINE-4-BORONIC ACID HYDRATE: CA 10-15% WATER (Pyridin-4-yl)boronic acid (may contain varying amounts of anhydride) B-4-Pyridinylboronic Acid Pyridine-4-boronic acid ,98% 4-Pyridylboronic Acid (contains varying amounts of Anhydride) Pyridine-4-boronic acid,97% 0Pyridine-4-boronicacid 4-Pyridinylboronic acid,4-Pyridineboronic acid Pyridine-4-boronica pyridin-4-ylboronic acid(SALTDATA: FREE) Pyridine-4-boronic acid wicker:lucywu Pyridine-4-boronic acid 97% PYRIDIN-4-YLBORONIC ACID 4-PYRIDINEBORONIC ACID 4-PYRIDYLBORONIC ACID 4-PYRIDINYLBORONIC ACID Pyridin-4-ylboronic acid, 97%, May contain varying aMounts of anhydride 1692-15-5 1692-16-5 1692-15-7 C5H6BNO2xH2O C5H7BNO2Cl C5H6BNO2 Heteroaryl Organometallic Reagents Boronic Acids and Derivatives Boronic Acids Heterocyclic Compounds B (Classes of Boron Compounds) blocks BoronicAcids Pyridines Boronic acid Organoborons Pyridine Miscellaneous Boronic Acids & Esters Boronic acids Aromatics Boron Derivatives Heterocycles