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5-HYDROXY ISATIN

CAS No.
116569-09-6
Chemical Name:
5-HYDROXY ISATIN
Synonyms
5-HYDROXY ISATIN;Flumazenil Impurity 17;5-hydroxyindoline-2,3-dione;5-Hydroxy-1H-indole-2,3-dione;1H-Indole-2,3-dione, 5-hydroxy-;5-hydroxy-2,3-dihydro-1H-indole-2,3-dione;5-Hydroxy isatin 5-Hydroxy indole-2,3-dione
CBNumber:
CB72455151
Molecular Formula:
C8H5NO3
Molecular Weight:
163.13
MDL Number:
MFCD11007925
MOL File:
116569-09-6.mol
MSDS File:
SDS
Last updated:2023-06-08 09:03:09

5-HYDROXY ISATIN Properties

storage temp. -20°C
solubility DMF: 3 mg/ml,DMSO: 5 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
form A solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P321-P305+P351+P338-P332+P313-P362+P364-P337+P313
NFPA 704
0
2 0

5-HYDROXY ISATIN price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 6895CR 5-Hydroxyindoline-2,3-dione 116569-09-6 2mg $218 2021-12-16 Buy
AK Scientific 6895CR 5-Hydroxyindoline-2,3-dione 116569-09-6 25mg $334 2021-12-16 Buy
American Custom Chemicals Corporation CHM0386196 5-HYDROXYISATIN 95.00% 116569-09-6 5MG $496.32 2021-12-16 Buy
AK Scientific 6895CR 5-Hydroxyindoline-2,3-dione 116569-09-6 2.5g $2895 2021-12-16 Buy
Product number Packaging Price Buy
6895CR 2mg $218 Buy
6895CR 25mg $334 Buy
CHM0386196 5MG $496.32 Buy
6895CR 2.5g $2895 Buy

5-HYDROXY ISATIN Chemical Properties,Uses,Production

Biological Activity

5-hydroxy Isatin is an inhibitor of monoamine oxidase A (MAO-A; IC50 = 8.4 μM).1 It is selective for MAO-A over MAO-B (IC50 = >100 μM). 5-hydroxy Isatin (50 μM) also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.2

References

1.Medvedev, A.E., Goodwin, B., Chow, A., et al.Inhibitory potency of some isatin analogues on human monoamine oxidase A and BBiochem. Pharmacol.44(3)590-592(1992) 2.Medvedev, A.E., Goodwin, B.L., Sandler, M., et al.Efficacy of isatin analogues as antagonists of rat brain and heart atrial natriuretic peptide receptors coupled to particulate guanylyl cyclaseBiochem. Pharmacol.57(8)913-915(1999)

5-HYDROXY ISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

5-HYDROXY ISATIN Suppliers

Global( 22)Suppliers
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Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52861 58
Nanjing Doge Biomedical Technology Co., Ltd
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PT CHEM GROUP LIMITED
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GIHI CHEMICALS CO.,LIMITED
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LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Shanghai Harvest Chemical Industrial Co., Ltd. 21-31038972 15721252604 ammyzuo@harvest-chem.com China 2540 64
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66099280 17798518460 cfzhang@aikonchem.com China 19918 55
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 18018 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
Shanghai Zhen Li Biological Technology Co., Ltd 021-16621358918; 18516310516 zhenlipharma888@163.com China 1992 58
5-HYDROXY ISATIN 5-Hydroxy-1H-indole-2,3-dione 5-hydroxyindoline-2,3-dione 5-Hydroxy isatin 5-Hydroxy indole-2,3-dione 1H-Indole-2,3-dione, 5-hydroxy- 5-hydroxy-2,3-dihydro-1H-indole-2,3-dione Flumazenil Impurity 17 116569-09-6