EzetiMibe-d4
- CAS No.
- 1093659-89-2
- Chemical Name:
- EzetiMibe-d4
- Synonyms
- Ezetimibe-d4-1;[2H4]-Ezetimibe;Ezetimibe Impurity 119;Ezetimibe D4 (4-Fluorophenyl-2,3,5,6-d4);(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl-2,3,5,6-d4)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one;(3R,4S)-3-[(3S)-3-[4-fluoro(2,3,5,6-2H?)phenyl]-3-hydroxypropyl]-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)azetidin-2-one;(3R,4S)-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)propyl]azetidin-2-one;Ezetimibe D4Q: What is Ezetimibe D4 Q: What is the CAS Number of Ezetimibe D4 Q: What is the storage condition of Ezetimibe D4
- CBNumber:
- CB72710005
- Molecular Formula:
- C24H21F2NO3
- Molecular Weight:
- 409.43
- MDL Number:
- MOL File:
- 1093659-89-2.mol
EzetiMibe-d4 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25044 | Ezetimibe-d4 ≥99% deuterated forms (d1-d4) | 1093659-89-2 | 1mg | $480 | 2024-03-01 | Buy |
| TRC | E975003 | Ezetimibe-d4 | 1093659-89-2 | 1mg | $275 | 2021-12-16 | Buy |
| AK Scientific | 2934DC | (3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)propyl]azetidin-2-one | 1093659-89-2 | 1mg | $633 | 2021-12-16 | Buy |
EzetiMibe-d4 Chemical Properties,Uses,Production
Description
Ezetimibe-d4 is intended for use as an internal standard for the quantification of ezetimibe by GC- or LC-MS. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Upon oral administration ezetimibe undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1. Ezetimibe exhibits ED50 values of 0.0005-0.05 mg/kg in various animal models, selectively blocking cholesterol absorption without inhibiting pancreatic lipolytic enzyme activities in the intestinal lumen, affecting bile acid micelle solubilization of cholesterol, or interfering with the absorption of triglycerides, fatty acids, or bile acids.
Uses
Ezetimibe-d4 is the labeled analogue of Ezetimibe (E975000), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.
EzetiMibe-d4 Preparation Products And Raw materials
Raw materials
Preparation Products
EzetiMibe-d4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| QUALITY CONTROL SOLUTIONS LTD. | 0755-66853366; 13670046396 | ORDERS@QCSRM.COM | China | 24342 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1955 | 55 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18146 | 56 |
| Artis Biotech Co. Ltd. | 19138486554 18108108965 | sales@artisbio.com | China | 5329 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Chengdu Novel Biomedical Co., Ltd. | 028-85255396 18302801538 | cdnovell@163.com | China | 2354 | 58 |
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