ChemicalBook >> CAS DataBase List >>tert-Butyl N-hydroxycarbamate
tert-Butyl N-hydroxycarbamate
- CAS No.
- 36016-38-3
- Chemical Name:
- tert-Butyl N-hydroxycarbamate
- Synonyms
- tert-Butyl hydroxycarbamate;N-BOC-HYDROXYLAMINE;BOC-NH-OH;BOC-HNOH;N-Boc-hydroxyL;BOC hydroxylamine;N-Boc-Hydroxyamine;N-hydroxycarbamate;N-T-BOC HYDROXYLAMINE;LABOTEST-BB LT00233206
- CBNumber:
- CB7274369
- Molecular Formula:
- C5H11NO3
- Molecular Weight:
- 133.15
- MDL Number:
- MFCD00002107
- MOL File:
- 36016-38-3.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Melting point | 53-55 °C (lit.) |
|---|---|
| Boiling point | 245.66°C (rough estimate) |
| Density | 1.2510 (rough estimate) |
| refractive index | 1.4120 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform, Methanol |
| pka | 9.31±0.23(Predicted) |
| form | Crystalline Powder |
| color | White to light pink |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Moisture Sensitive |
| BRN | 1756546 |
| InChI | InChI=1S/C5H11NO3/c1-5(2,3)9-4(7)6-8/h8H,1-3H3,(H,6,7) |
| InChIKey | DRDVJQOGFWAVLH-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)NO |
| CAS DataBase Reference | 36016-38-3(CAS DataBase Reference) |
| FDA UNII | GJV9GPX5T3 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280-P261 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 21 | |||||||||
| HS Code | 29280090 | |||||||||
| NFPA 704 |
|
tert-Butyl N-hydroxycarbamate price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 226157 | N-Boc-hydroxylamine ≥98% | 36016-38-3 | 5g | $97.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 226157 | N-Boc-hydroxylamine ≥98% | 36016-38-3 | 1g | $26 | 2023-06-20 | Buy |
| TCI Chemical | H0848 | tert-Butyl N-Hydroxycarbamate >98.0%(GC) | 36016-38-3 | 5g | $17 | 2024-03-01 | Buy |
| TCI Chemical | H0848 | tert-Butyl N-Hydroxycarbamate >98.0%(GC) | 36016-38-3 | 25g | $34 | 2024-03-01 | Buy |
| Alfa Aesar | A10349 | N-Boc-hydroxylamine, 98+% | 36016-38-3 | 1g | $27.65 | 2024-03-01 | Buy |
tert-Butyl N-hydroxycarbamate Chemical Properties,Uses,Production
Chemical Properties
White to light pink crystalline powder
Uses
tert-Butyl N-hydroxycarbamate is used in the preparation of azridines by cycloaddition of azides with nitroso Diels-Alder adducts.
Uses
N-Boc-hydroxylamine is used in the preparation of azridines by cycloaddition of azides with nitroso Diels-Alder adducts. It acts as a reagent for the synthesis of hydroxylamine derivatives t-butyl-N-(acyloxy)carbamates and N,O-diacylated N-hydroxyarylsulfonamides.
Synthesis Reference(s)
Journal of the American Chemical Society, 81, p. 955, 1959 DOI: 10.1021/ja01513a049
Tetrahedron Letters, 24, p. 231, 1983 DOI: 10.1016/S0040-4039(00)81372-6
Synthesis
A suspension of NH2OH·HCl (9.7 g, 140mmol) and K2CO3 (9.7 g, 700 mmol) in Et2O (60 mL) and H2O (2 mL)was stirred for about 1 h at r.t. with evolution of CO2 gas. A solution of Boc2O (20.0 g, 92 mmol) in Et2O (40 mL) was then added dropwise at 0 °C, and the suspension was stirred at r.t for 12 h. The organic phase was decanted, and the solid was washed with Et2O (3 × 30 mL). The combined organic layers were concentrated, and the residue was recrystallized from cyclohexane/toluene to afford the desired product tert-butyl N-hydroxycarbamate as a white solid.
tert-Butyl N-hydroxycarbamate Preparation Products And Raw materials
Global( 401)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xiamen Yunfan Biotech Co.,Ltd. | +8618050056030 | yezhaobao@yfpharm.com | China | 27 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20262 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29792 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18949 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | FandaChem@Gmail.com | China | 8441 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32965 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29871 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
View Lastest Price from tert-Butyl N-hydroxycarbamate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-09-26 | tert-Butyl N-hydroxycarbamate
36016-38-3
|
US $0.00-0.00 / kg | 1kg | 99%+ | 1200kg/Month | Xiamen Yunfan Biotech Co.,Ltd. | |
 |
2024-08-27 | tert-Butyl N-hydroxycarbamate
36016-38-3
|
US $70.00-700.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2024-04-09 | tert-Butyl N-hydroxycarbamate
36016-38-3
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- tert-Butyl N-hydroxycarbamate
36016-38-3
- US $0.00-0.00 / kg
- 99%+
- Xiamen Yunfan Biotech Co.,Ltd.
-
- tert-Butyl N-hydroxycarbamate
36016-38-3
- US $70.00-700.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- tert-Butyl N-hydroxycarbamate
36016-38-3
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
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tert-Butyl N-hydroxycarbamate
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BOC-Hydroxylamine Tert-Butyl N-hydroxycarbamate
Carbamic acid,N-hydroxy-, 1,1-dimethylethyl ester
N-Boc-hydroxylamine≥ 99% (HPLC)
N-tert-BOC-Hydroxylamine for synthesis
N-(tert-Butoxycarbonyl)hyd
BOC hydroxylamine
4-hydroxy-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]butanoic acid
n-hydroxycarbamate tert butyl ester
tert-ButylN-Hydroxycarbamate>
N-Boc-hydroxyL
N-hydroxycarbamate
ert-ButylN-hydroxycarbamate
N-tert-Boc-Hydroxylamine
N-BOC-HYDROXYLAMINE
tert-Butyl hydroxycarbamate
BOC-NH-OH
(t-Butoxycarbonyl)-hydroxylamine
N-Hydroxy-N-tert-butyloxycarbonylamide
36016-38-3
C5H11O3N
CH33COCONHOH
Hydroxylamines
Hydroxylamines (N-Substituted)
Building Blocks
Organic Building Blocks
Nitrogen Compounds
Protected Amines
Hydroxylamines
Hydroxylamines (N-Substituted)
Naphthyridine,Quinoline
API intermediates
INTERMEDIATESOFMEROPENAM
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