tert-Butyl N-hydroxycarbamate
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tert-Butyl N-hydroxycarbamate 속성
- 녹는점
- 53-55 °C (lit.)
- 끓는 점
- 245.66°C (rough estimate)
- 밀도
- 1.2510 (rough estimate)
- 굴절률
- 1.4120 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름, 메탄올에 용해됨
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 9.31±0.23(Predicted)
- 색상
- 흰색에서 밝은 분홍색까지
- 수용성
- 물에 약간 용해됩니다.
- 감도
- Moisture Sensitive
- BRN
- 1756546
- InChI
- InChI=1S/C5H11NO3/c1-5(2,3)9-4(7)6-8/h8H,1-3H3,(H,6,7)
- InChIKey
- DRDVJQOGFWAVLH-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NO
- CAS 데이터베이스
- 36016-38-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
tert-Butyl N-hydroxycarbamate C화학적 특성, 용도, 생산
화학적 성질
White to light pink crystalline powder용도
tert-Butyl N-hydroxycarbamate is used in the preparation of azridines by cycloaddition of azides with nitroso Diels-Alder adducts.Synthesis Reference(s)
Journal of the American Chemical Society, 81, p. 955, 1959 DOI: 10.1021/ja01513a049Tetrahedron Letters, 24, p. 231, 1983 DOI: 10.1016/S0040-4039(00)81372-6
Synthesis
A suspension of NH2OH·HCl (9.7 g, 140mmol) and K2CO3 (9.7 g, 700 mmol) in Et2O (60 mL) and H2O (2 mL)was stirred for about 1 h at r.t. with evolution of CO2 gas. A solution of Boc2O (20.0 g, 92 mmol) in Et2O (40 mL) was then added dropwise at 0 °C, and the suspension was stirred at r.t for 12 h. The organic phase was decanted, and the solid was washed with Et2O (3 × 30 mL). The combined organic layers were concentrated, and the residue was recrystallized from cyclohexane/toluene to afford the desired product tert-butyl N-hydroxycarbamate as a white solid.tert-Butyl N-hydroxycarbamate 준비 용품 및 원자재
원자재
준비 용품
tert-Butyl N-hydroxycarbamate 공급 업체
글로벌( 394)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Xiamen Yunfan Biotech Co.,Ltd. | +8618050056030 |
yezhaobao@yfpharm.com | China | 27 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 10991 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20291 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9284 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 |
stella@zetchem.com | China | 2136 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |