ChemicalBook >> CAS DataBase List >>FGTI-2734
FGTI-2734
- CAS No.
- 1247018-19-4
- Chemical Name:
- FGTI-2734
- Synonyms
- FGTI-2734;2-Pyridinesulfonamide, N-[2-[(4-cyano-2-fluorophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino]ethyl]-N-(cyclohexylmethyl)-;pancreatic,patient-derived,geranylgeranyl,farnesyl,inhibit,Farnesyl Transferase,mimetic,FGTI2734,Inhibitor,membrane,Ftase,FGTI-2734,KRAS,FGTI 2734,C-terminal,transferase,tumors,localization
- CBNumber:
- CB75540586
- Molecular Formula:
- C26H31FN6O2S
- Molecular Weight:
- 510.63
- MDL Number:
- MFCD32174296
- MOL File:
- 1247018-19-4.mol
Last updated:2024-07-02 08:55:17
FGTI-2734 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0099052 | FGTI-2734 99.48% | 1247018-19-4 | 5mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0099052 | FGTI-2734 99.48% | 1247018-19-4 | 10mg | $650 | 2021-12-16 | Buy |
| ChemScene | CS-0099052 | FGTI-2734 99.48% | 1247018-19-4 | 50mg | $2000 | 2021-12-16 | Buy |
| ChemScene | CS-0099052 | FGTI-2734 99.48% | 1247018-19-4 | 100mg | $3500 | 2021-12-16 | Buy |
| DC Chemicals | DC32723 | FGTI-2734 | 1247018-19-4 | 100mg | $1300 | 2021-12-16 | Buy |
FGTI-2734 Chemical Properties,Uses,Production
Description
FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor. It can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors.
target
FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT-1, respectively.
Synthesis of FGTI-2734 from 2-Pyridinesulfonamide, N-[2-[(4-cyano-2-fluorophenyl)amino]ethyl]-N-(cyclohexylmethyl)- and MFCD08668158
FGTI-2734 Preparation Products And Raw materials
Raw materials
Preparation Products
FGTI-2734 Suppliers
Global( 16)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9887 | 58 |
| Shanghai Dongyang Biotechnology Co., Ltd. | 0512-0512-13601744364 13601744364 | chemsharker@126.com | China | 893 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9412 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
FGTI-2734
2-Pyridinesulfonamide, N-[2-[(4-cyano-2-fluorophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino]ethyl]-N-(cyclohexylmethyl)-
pancreatic,patient-derived,geranylgeranyl,farnesyl,inhibit,Farnesyl Transferase,mimetic,FGTI2734,Inhibitor,membrane,Ftase,FGTI-2734,KRAS,FGTI 2734,C-terminal,transferase,tumors,localization
1247018-19-4
C26H31FN6O2S