C-JUN N-TERMINAL KINASE
- CAS No.
- Chemical Name:
- C-JUN N-TERMINAL KINASE
- Synonyms
- JNK3;JNK3A;MAPK10;PRKM10;p493F12;FLJ33785;FLJ12099;MGC50974;p54bSAPK;SAPK1B/JNK3
- CBNumber:
- CB7769250
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01635905
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Safety Statements | 23-24/25 |
|---|---|
| WGK Germany | 1 |
C-JUN N-TERMINAL KINASE price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB1412174 | ANTI-MAPK10 antibody produced in mouse clone 3A3-1A8, purified immunoglobulin, buffered aqueous solution | 100μg | $524 | 2024-03-01 | Buy | |
| Biorbyt Ltd | orb529641 | MAPK10 | 10μg | $579.7 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb596871 | MAPK10 | 10μg | $290.7 | 2021-12-16 | Buy | |
| American Custom Chemicals Corporation | PRO0004497 | JNK3 95.00% | 5MG | $503.91 | 2021-12-16 | Buy |
C-JUN N-TERMINAL KINASE Chemical Properties,Uses,Production
Uses
JNK-3 is an inhibitor of JNK kinase which may be used in the treatment of many hyperactive JNK signaling diseases such as cancer, inflammatory diseases and neurodegenerative diseases.
General Description
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq)
C-JUN N-TERMINAL KINASE Preparation Products And Raw materials
Raw materials
Preparation Products
C-JUN N-TERMINAL KINASE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd | 18072846723; 18072846723 | caigou1@witofly.com | China | 18919 | 58 |
| Supplier | Advantage |
|---|---|
| Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd | 58 |