C-JUN N-TERMINAL KINASE

C-JUN N-TERMINAL KINASE C화학적 특성, 용도, 생산

용도

JNK-3 is an inhibitor of JNK kinase which may be used in the treatment of many hyperactive JNK signaling diseases such as cancer, inflammatory diseases and neurodegenerative diseases.

일반 설명

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq)

C-JUN N-TERMINAL KINASE 준비 용품 및 원자재

원자재

준비 용품

C-JUN N-TERMINAL KINASE 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hangzhou Lianke Biotechnology Co., Ltd.	--		CHINA	6349	58
Shanghai Haoran Biotechnology Co., Ltd.	--	470003480@QQ.COM	CHINA	6968	58
Nanjing Shanben Biotechnology Co., Ltd.	--	sales@sciben.com	CHINA	6053	58
Beijing Huaxia Ocean Technology Co., Ltd.	--	huaxiabio@163.com	CHINA	6122	58
Shanghai Boyi Biotechnology Co., Ltd.	--	15800446246@163.com	CHINA	5417	58
Riedel-de Haen AG	--		United States	6825	87
SIGMA-RBI	--		Switzerland	6913	91
BIOMOL INTERNATIONAL, LP	--	info@biomol.com	United States	1503	77
Upstate	--	info@upstate.com	United States	876	76