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JM 221

CAS No.
129551-91-3
Chemical Name:
JM 221
Synonyms
JM 221
CBNumber:
CB81312469
Molecular Formula:
C8H14Cl2O4Pt.C6H13N.H3N
Molecular Weight:
556.387
MDL Number:
MOL File:
129551-91-3.mol
Last updated:2023-03-31 09:12:57

JM 221 Chemical Properties,Uses,Production

Description

JM-221 is a novel platinum(IV) dicarboxylate complex exhibiting enhanced cytotoxicity in human ovarian carcinoma cell line when compared to Cisplatin. Comparison with platinum accumulation from Cisplatin suggests that the increased cytotoxicity of JM-221 may be related_x000D_ to increased accumulation within the cell. JM-221 is more lipophilic than Cisplatin, which may account for improved uptake in Cisplatin resistant cells.

JM 221 Preparation Products And Raw materials

Raw materials

Preparation Products

JM 221 129551-91-3