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JM 221
- CAS No.
- 129551-91-3
- Chemical Name:
- JM 221
- Synonyms
- JM 221
- CBNumber:
- CB81312469
- Molecular Formula:
- C8H14Cl2O4Pt.C6H13N.H3N
- Molecular Weight:
- 556.387
- MDL Number:
- MOL File:
- 129551-91-3.mol
Last updated:2023-03-31 09:12:57
JM 221 Chemical Properties,Uses,Production
Description
JM-221 is a novel platinum(IV) dicarboxylate complex exhibiting enhanced cytotoxicity in human ovarian carcinoma cell line when compared to Cisplatin. Comparison with platinum accumulation from Cisplatin suggests that the increased cytotoxicity of JM-221 may be related_x000D_ to increased accumulation within the cell. JM-221 is more lipophilic than Cisplatin, which may account for improved uptake in Cisplatin resistant cells.
JM 221 Preparation Products And Raw materials
Raw materials
Preparation Products
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JM 221
129551-91-3