ChemicalBook >> CAS DataBase List >>NQ301
NQ301
- CAS No.
- 130089-98-4
- Chemical Name:
- NQ301
- Synonyms
- NQ301;NQ 301; NQ-301;NQ301 >=98% (HPLC);NQ301 - Compound 211;NQ301, 10 mM in DMSO;inhibit,Inhibitor,NQ-301,NQ301,NQ 301,Thrombin;2-(4-Acetylanilino)-3-chloronaphthalene-1,4-dione;2-((4-acetylphenyl)amino)-3-chloronaphthalene-1,4-dione;2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione;1,4-Naphthalenedione, 2-[(4-acetylphenyl)amino]-3-chloro-
- CBNumber:
- CB81352274
- Molecular Formula:
- C18H12ClNO3
- Molecular Weight:
- 325.75
- MDL Number:
- MFCD00559986
- MOL File:
- 130089-98-4.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Melting point | 241-243 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 476.8±45.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO:10.0(Max Conc. mg/mL);30.7(Max Conc. mM) |
| pka | -5.25±0.20(Predicted) |
| form | powder |
| color | faint red to dark red |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H400 | |||||||||
| Precautionary statements | P273-P280-P304+P340+P312-P305+P351+P338-P337+P313-P391 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| NFPA 704 |
|
NQ301 price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1337 | NQ301 ≥98% (HPLC) | 130089-98-4 | 5mg | $118 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1337 | NQ301 ≥98% (HPLC) | 130089-98-4 | 25mg | $370 | 2024-03-01 | Buy |
| Cayman Chemical | 21958 | NQ301 | 130089-98-4 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21958 | NQ301 | 130089-98-4 | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 21958 | NQ301 | 130089-98-4 | 10mg | $139 | 2024-03-01 | Buy |
NQ301 Chemical Properties,Uses,Production
Uses
NQ 301 possess antiplatelet effect, making it an antithrombotic agent. It significantly inhibited the collagen-?, thrombin-?, arachidonic acid-?, thapsigargin- and calcium ionophore A23187-?induced aggregation of washed human platelets.
Biochem/physiol Actions
NQ301 is an antithrombotic agent. Recent study shows that NQ301 (Compound 211) is a highly potent, selective, non-competitive allosteric inhibitor of CD45 that selectively inhibits dephosphorylation of substrate Lck pY-505 versus Lck pY-393. NQ301 prevents T cell receptor-mediated activation of Lck, Zap-70 and MAPK, and IL-2 production in primary T-cells. NQ301 exhibits immunosuppressive activity in mice.
NQ301 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 69)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32965 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14055 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
NQ301
NQ301 - Compound 211
NQ 301; NQ-301
2-((4-acetylphenyl)amino)-3-chloronaphthalene-1,4-dione
2-(4-Acetylanilino)-3-chloronaphthalene-1,4-dione
2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione
1,4-Naphthalenedione, 2-[(4-acetylphenyl)amino]-3-chloro-
NQ301 >=98% (HPLC)
inhibit,Inhibitor,NQ-301,NQ301,NQ 301,Thrombin
NQ301, 10 mM in DMSO
130089-98-4