5,7,8,4''-TETRAMETHOXYFLAVONE
- CAS No.
- 6601-66-7
- Chemical Name:
- 5,7,8,4''-TETRAMETHOXYFLAVONE
- Synonyms
- 8-Tetramethoxyflavone;tetramethylisoscutellarein;5,7,8,4'-Tetramethoxyflavone;4’,5,7,8-Tetramethoxyflavone;5,7,8-trimethoxy-2-(4-methoxyphenyl)chromen-4-one;5,7,8,4'- tetramethoxyflavone 6-Demethoxytangeretin;5,7,8-Trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one;4H-1-Benzopyran-4-one, 5,7,8-trimethoxy-2-(4-methoxyphenyl)-;Cluster of differentiation 246,6Demethoxytangeretin,Anaplastic lymphoma kinase (ALK),Anaplastic lymphoma kinase,6-Demethoxytangeretin,CD246,inhibit,ALK tyrosine kinase receptor,6 Demethoxytangeretin,Inhibitor
- CBNumber:
- CB81484236
- Molecular Formula:
- C19H18O6
- Molecular Weight:
- 342.34
- MDL Number:
- MFCD03427696
- MOL File:
- 6601-66-7.mol
| Melting point | 216-217℃ (methanol ) |
|---|---|
| Boiling point | 536.9±50.0 °C(Predicted) |
| Density | 1.243±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO |
| form | Solid |
| color | White to off-white |
| FDA UNII | 2U2U884D0P |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
5,7,8,4''-TETRAMETHOXYFLAVONE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FT65329 | 5,7,8,4'-Tetramethoxyflavone | 6601-66-7 | 1mg | $195 | 2021-12-16 | Buy |
| ChemScene | CS-0032143 | 6-Demethoxytangeretin 99.28% | 6601-66-7 | 5mg | $202 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FT65329 | 5,7,8,4'-Tetramethoxyflavone | 6601-66-7 | 2mg | $300 | 2021-12-16 | Buy |
| ChemScene | CS-0032143 | 6-Demethoxytangeretin 99.28% | 6601-66-7 | 10mg | $343 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FT65329 | 5,7,8,4'-Tetramethoxyflavone | 6601-66-7 | 5mg | $625 | 2021-12-16 | Buy |
5,7,8,4''-TETRAMETHOXYFLAVONE Chemical Properties,Uses,Production
Uses
6-Demethoxytangeretin is a flavonoid compound that can be isolated from Citrus reticulata. 6-Demethoxytangeretin has anti-inflammatory and anti-allergic activities and can inhibit the production of IL-6 and the expression of related genes in human mast cells through the ALK and MAPK pathways. 6-Demethoxytangeretin can promote CRE-mediated transcription in hippocampal neurons[1][2].
References
[1] Kim YM, et al. A citrus flavonoid, 6-demethoxytangeretin, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase and mitogen-activated protein kinase pathways. Biol Pharm Bull. 2014;37(5):871-6. Epub 2014 Feb 5. DOI:10.1248/bpb.b13-00875
[2] Kawahata I, et al. Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action. J Neural Transm (Vienna). 2013 Oct;120(10):1397-409. DOI:10.1007/s00702-013-1025-x
5,7,8,4''-TETRAMETHOXYFLAVONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
View Lastest Price from 5,7,8,4''-TETRAMETHOXYFLAVONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-17 | 6-Demethoxytangeretin
6601-66-7
|
US $54.00-198.00 / mg | 99.89% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | 6-Demethoxytangeretin
6601-66-7
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2020-01-13 | 5,7,8,4''-TETRAMETHOXYFLAVONE
6601-66-7
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- 6-Demethoxytangeretin
6601-66-7
- US $54.00-198.00 / mg
- 99.89%
- TargetMol Chemicals Inc.
-
- 6-Demethoxytangeretin
6601-66-7
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- 5,7,8,4''-TETRAMETHOXYFLAVONE
6601-66-7
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co