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ChemicalBook >> CAS DataBase List >>N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Structure
N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide structure
CAS No.
918505-61-0
Chemical Name:
N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
Synonyms
CS-1029;PLX 4032;INXN-1001;ZELBORAF.(R).;BRAF inhibitor;PLX-4032(RG7204);Vemurafenib-Analog;Raf kinases,inhibit,Inhibitor,BRAF inhibitor,Raf;N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin...;N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide
CBNumber:
CB82489948
Molecular Formula:
C22H18F2N4O3S
Molecular Weight:
456.47
MDL Number:
MFCD16659048
MOL File:
918505-61-0.mol
MSDS File:
SDS
Last updated:2024-07-02 08:55:20
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N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Properties

Density 1.45
storage temp. Store at -20°C
solubility DMSO : 50 mg/mL (109.54 mM; Need ultrasonic)
form Powder
pka 6.54±0.10(Predicted)
color White to off-white
NCI Dictionary of Cancer Terms PLX4032

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P305+P351+P338

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FV15248 PLX 4032 918505-61-0 50mg $75 2021-12-16 Buy
Biosynth Carbosynth FV15248 PLX 4032 918505-61-0 100mg $100 2021-12-16 Buy
ChemScene CS-0055 BRAFinhibitor 98.61% 918505-61-0 10mg $180 2021-12-16 Buy
Biosynth Carbosynth FV15248 PLX 4032 918505-61-0 250mg $187.5 2021-12-16 Buy
ApexBio Technology A3263 BRAFinhibitor 918505-61-0 10mg $293 2021-12-16 Buy
Product number Packaging Price Buy
FV15248 50mg $75 Buy
FV15248 100mg $100 Buy
CS-0055 10mg $180 Buy
FV15248 250mg $187.5 Buy
A3263 10mg $293 Buy

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Chemical Properties,Uses,Production

Uses

Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Potent B-Raf inhibitor

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Suppliers

Global( 95)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29798 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32760 60
Shanghai Arbor Chemical Co., Ltd. 		021-60451682 act@arborchemical.com CHINA 906 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10259 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49391 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29826 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Allfluoro pharmaceutical co. ltd. 		021-26137118 +8615821363818 sales@allfluoro.com China 5791 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23556 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Shanghai Arbor Chemical Co., Ltd. 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
Allfluoro pharmaceutical co. ltd. 		58
ANHUI WITOP BIOTECH CO., LTD 		58

View Lastest Price from N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide pictures 2020-01-09 N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
918505-61-0
 US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide Spectrum

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide(918505-61-0)1HNMR
PLX-4032(RG7204) N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)phenyl)propane-2-sulfinamide PLX 4032 BRAF inhibitor ZELBORAF.(R). 2-PropanesulfonaMide, N-[2,4-difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]- N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfin N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sul N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide CS-1029 Vemurafenib-Analog N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin... INXN-1001 Raf kinases,inhibit,Inhibitor,BRAF inhibitor,Raf 918505-61-0 C22H18F2N4O3S