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ChemicalBook >> CAS DataBase List >> N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide

N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide price.
  • $75 - $3825.15
  • Product name: N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
  • CAS: 918505-61-0
  • MF: C22H18F2N4O3S
  • MW: 456.47
  • EINECS:
  • MDL Number:MFCD16659048
  • Synonyms:PLX-4032(RG7204);N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)phenyl)propane-2-sulfinamide;PLX 4032;BRAF inhibitor;ZELBORAF.(R).;2-PropanesulfonaMide, N-[2,4-difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-;N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide;N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfin
Price22 Properties Safety Information Description
22 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 5MG
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1G
  • 2g
  • 5G
  • 10g
  • ManufacturerAK Scientific
  • Product number5506AC
  • Product descriptionBRAFinhibitor
  • Packaging250mg
  • Price$2577
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0316612
  • Product descriptionN-[2,4-DIFLUORO-3-[[5-(3-PYRIDINYL)-1H-PYRROLO[2,3-B]PYRIDIN-3-YL]CARBONYL]PHENYL]-2-PROPANESULFONAMIDE 95.00%
  • Packaging5MG
  • Price$505.46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0316612
  • Product descriptionN-[2,4-DIFLUORO-3-[[5-(3-PYRIDINYL)-1H-PYRROLO[2,3-B]PYRIDIN-3-YL]CARBONYL]PHENYL]-2-PROPANESULFONAMIDE 95.00%
  • Packaging1G
  • Price$3825.15
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3263
  • Product descriptionBRAFinhibitor
  • Packaging10mg
  • Price$293
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3263
  • Product descriptionBRAFinhibitor
  • Packaging50mg
  • Price$820
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV15248
  • Product descriptionPLX 4032
  • Packaging50mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV15248
  • Product descriptionPLX 4032
  • Packaging100mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV15248
  • Product descriptionPLX 4032
  • Packaging250mg
  • Price$187.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV15248
  • Product descriptionPLX 4032
  • Packaging500mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD34276
  • Product descriptionN-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide
  • Packaging500mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV15248
  • Product descriptionPLX 4032
  • Packaging1g
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD34276
  • Product descriptionN-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide
  • Packaging1g
  • Price$525
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD34276
  • Product descriptionN-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide
  • Packaging2g
  • Price$630
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD34276
  • Product descriptionN-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide
  • Packaging5G
  • Price$1260
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD34276
  • Product descriptionN-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide
  • Packaging10g
  • Price$2100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM173682
  • Product descriptionN-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfinamide 95%+
  • Packaging50mg
  • Price$342
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5506AC BRAFinhibitor 250mg $2577 2021-12-16 Buy
American Custom Chemicals Corporation HCH0316612 N-[2,4-DIFLUORO-3-[[5-(3-PYRIDINYL)-1H-PYRROLO[2,3-B]PYRIDIN-3-YL]CARBONYL]PHENYL]-2-PROPANESULFONAMIDE 95.00% 5MG $505.46 2021-12-16 Buy
American Custom Chemicals Corporation HCH0316612 N-[2,4-DIFLUORO-3-[[5-(3-PYRIDINYL)-1H-PYRROLO[2,3-B]PYRIDIN-3-YL]CARBONYL]PHENYL]-2-PROPANESULFONAMIDE 95.00% 1G $3825.15 2021-12-16 Buy
ApexBio Technology A3263 BRAFinhibitor 10mg $293 2021-12-16 Buy
ApexBio Technology A3263 BRAFinhibitor 50mg $820 2021-12-16 Buy
Biosynth Carbosynth FV15248 PLX 4032 50mg $75 2021-12-16 Buy
Biosynth Carbosynth FV15248 PLX 4032 100mg $100 2021-12-16 Buy
Biosynth Carbosynth FV15248 PLX 4032 250mg $187.5 2021-12-16 Buy
Biosynth Carbosynth FV15248 PLX 4032 500mg $300 2021-12-16 Buy
Biosynth Carbosynth FD34276 N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide 500mg $315 2021-12-16 Buy
Biosynth Carbosynth FV15248 PLX 4032 1g $500 2021-12-16 Buy
Biosynth Carbosynth FD34276 N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide 1g $525 2021-12-16 Buy
Biosynth Carbosynth FD34276 N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide 2g $630 2021-12-16 Buy
Biosynth Carbosynth FD34276 N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide 5G $1260 2021-12-16 Buy
Biosynth Carbosynth FD34276 N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-2-propanesulfonamide 10g $2100 2021-12-16 Buy
Chemenu CM173682 N-(2,4-Difluoro-3-(5-(pyridin-3-yl)-1H-pyrrolo[2,3-b]-pyridine-3-carbonyl)phenyl)propane-2-sulfinamide 95%+ 50mg $342 2021-12-16 Buy
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Properties

Density :1.45
storage temp. :Store at -20°C
solubility :DMSO : 50 mg/mL (109.54 mM; Need ultrasonic)
form :Powder
pka :6.54±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Potent B-Raf inhibitor

Suppliers and manufacturers

career henan chemical co
N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide
$9.80 /1.79999995231628KG
N-[2,4-Difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-2-propanesulfonamide CAS:918505-61-0
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Shanghai Arbor Chemical Co., Ltd.
Shenzhen Nexconn Pharmatechs Ltd
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED
TargetMol Chemicals Inc.
Allfluoro pharmaceutical co. ltd.
ANHUI WITOP BIOTECH CO., LTD