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Largazole

Largazole Structure
Largazole structure
CAS No.
1009815-87-5
Chemical Name:
Largazole
Synonyms
Largazole;(+)-largazole;AXESYCSCGBQJBL-SZPBEECKSA-N;Octanethioic acid, S-[(3E)-4-[(5R,8S,11S)-5-methyl-8-(1-methylethyl)-6,9,13-trioxo-10-oxa-3,17-dithia-7,14,19,20-tetraazatricyclo[14.2.1.12,5]eicosa-2(20),16(19),18-trien-11-yl]-3-buten-1-yl] ester
CBNumber:
CB82519128
Molecular Formula:
C29H42N4O5S3
Molecular Weight:
622.86
MDL Number:
MFCD18074512
MOL File:
1009815-87-5.mol
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Largazole Properties

Density 1.31±0.1 g/cm3(Predicted)
storage temp. Storage at -20℃
pka 12.12±0.70(Predicted)

Largazole price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC L176005 Largazole 1009815-87-5 0.5mg $965 2021-12-16 Buy
TRC L176005 Largazole 1009815-87-5 2.5mg $3275 2021-12-16 Buy
American Custom Chemicals Corporation API0024276 LARGAZOLE 95.00% 1009815-87-5 5MG $496.99 2021-12-16 Buy
Product number Packaging Price Buy
L176005 0.5mg $965 Buy
L176005 2.5mg $3275 Buy
API0024276 5MG $496.99 Buy

Largazole Chemical Properties,Uses,Production

Uses

Largazole is a potent and selective histone deacetylase (HDAC) inhibitor.

Uses

Largazole is derived from cyanobacteria that grow on coral reefs, which may have potentials as an anti-cancer drug. Largazole is a potent histone deacetylase inhibitor. [1] Largazole has its potent antiproliferative activity against a number of cancer cell-lines including MDA-MB-231 mammary cells (GI50 7.7 nM), U2OS fibroblastic osteosarcoma cells (GI50 55 nM), HT29 colon cells (GI50 12 nM), and IMR-32 neuroblastoma cells (GI50 16 nM).

Largazole Preparation Products And Raw materials

Raw materials

Preparation Products

Largazole Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Chizhou Kailong Import and Export Trade Co., Ltd. xg01_gj@163.com China 9503 50
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Chizhou Kailong Import and Export Trade Co., Ltd. 50
TargetMol Chemicals Inc. 58
Largazole Octanethioic acid, S-[(3E)-4-[(5R,8S,11S)-5-methyl-8-(1-methylethyl)-6,9,13-trioxo-10-oxa-3,17-dithia-7,14,19,20-tetraazatricyclo[14.2.1.12,5]eicosa-2(20),16(19),18-trien-11-yl]-3-buten-1-yl] ester AXESYCSCGBQJBL-SZPBEECKSA-N (+)-largazole 1009815-87-5 C29H42N4O5S3