Ervamycine
- CAS No.
- 27773-39-3
- Chemical Name:
- Ervamycine
- Synonyms
- Ervamycine;VincamineImpurity20;16-Methoxytabersonine;Tabersonine Impurity 3;Vincamine Impurity 20 (Ervamycine);Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-16-methoxy-, methyl ester, (5α,12R,19α)-
- CBNumber:
- CB82519724
- Molecular Formula:
- C22H26N2O3
- Molecular Weight:
- 366.46
- MDL Number:
- MFCD20260708
- MOL File:
- 27773-39-3.mol
Boiling point | 514.6±50.0 °C(Predicted) |
---|---|
Density | 1.27±0.1 g/cm3(Predicted) |
pka | 7.66±0.60(Predicted) |
FDA UNII | VX294XSR6T |
Ervamycine price
Ervamycine Chemical Properties,Uses,Production
Description
This alkaloid from Vinca herbacea has been isolated as the crystalline hydrochloride, m.p. 184-6°C (dec.). The free base has [α]23D - 310° ± 2° (c 0.32, CHC13). Hydrogenation over Pt02 gives the 6:7-dihydro derivative which has [α]26D - 412.8° (c 0.606, CHCI3). When heated at 100°C with 5N-HC1, the latter is simultaneously hydrolyzed and decarboxylated to furnish 16-methoxy- 1: 2-dehydro-( - )-aspidospermidine.
Definition
ChEBI: 16-methoxytabersonine is the 16-methoxy derivative of tabersonine. It is a monoterpenoid indole alkaloid, an organic heteropentacyclic compound, a methyl ester and a tertiary amino compound. It is functionally related to a tabersonine. It is a conjugate base of a 16-methoxytabersoninium(1+).
References
Pyuskyulev et al., Collect. Czech. Chem. Commun., 32, 1289 (1967)
Ervamycine Preparation Products And Raw materials
Raw materials
Preparation Products
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